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Merck

53519-U

Supelco

Ascentis® Express 90 Å RP-Amide (2.7 μm) HPLC Columns

L × I.D. 5 mm × 4.6 mm, HPLC Guard Cartridge, pkg of 3 ea

Synonym(e):

Core-shell (SPP) Fused Core polar embedded HPLC column

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Ascentis® Express RP-Amid, 2,7-μm-Schutzkartusche, 2.7 μm particle size, L × I.D. 5 mm × 4.6 mm, pkg of 3 ea

Materialien

stainless steel column

Qualitätsniveau

Agentur

suitable for USP L60

Produktlinie

Ascentis®

Leistungsmerkmale

endcapped

Verpackung

pkg of 3 ea

Methode(n)

HPLC: suitable
LC/MS: suitable

L × ID

5 mm × 4.6 mm

Oberflächenbereich

135 m2/g

Matrix

Fused-Core® particle platform
superficially porous particle

Aktive Matrixgruppe

amide, alkyl phase

Partikelgröße

2.7 μm

Porengröße

90 Å

Betriebs-pH-Wert

2-9

Anwendung(en)

food and beverages

Trenntechnik

reversed phase

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Verwandte Kategorien

Allgemeine Beschreibung

Ascentis Express Vorsäulen bieten physischen (Filtration) und chemischen Schutz für teure Analysesäulen, ohne die sehr hohe Leistung der Ascentis Express Säulen zu beeinträchtigen. Diese Ascentis Express Vorsäulen eignen sich für den Dauereinsatz bei einem Druck von bis zu 600 bar und müssen lediglich handfest angezogen werden. Die Vorsäulen lassen sich mühelos austauschen, ohne den Vorsäulenhalter vom Flusspfad entfernen zu müssen. Die Kartuschen sind mit Ascentis Express Fused-Core® Partikeln gepackt. Der Vorsäulenhalter ist separat zu bestellen.

Anwendung


  • Polycaprolactone Composite Micro/Nanofibrous Material as an Alternative to Restricted Access Media for Direct Extraction and Separation of Non-Steroidal Anti-Inflammatory Drugs from Human Serum Using Column-Switching Chromatography: This research utilized the Ascentis Express RP-Amide, demonstrating its effectiveness in column-switching chromatography for the extraction and separation of non-steroidal anti-inflammatory drugs directly from human serum. The study highlights the column′s utility in handling complex biological matrices, an essential aspect for pharmacokinetic and drug monitoring studies (Raabova et al., 2021).

  • An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study: This paper details the use of the Ascentis Express RP-Amide in a validated HPLC-MS method for the analysis of PC 48, a novel acetylcholinesterase inhibitor, in rat plasma. The method′s application to pharmacokinetic studies underscores its significance in the development and therapeutic monitoring of new drugs (Mzik et al., 2016).

  • On-line SPE-UHPLC method using fused core columns for extraction and separation of nine illegal dyes in chilli-containing spices: Demonstrating the versatility of the Ascentis Express RP-Amide, this study employed the column in an on-line solid-phase extraction (SPE) coupled with UHPLC to detect illegal dyes in food samples. The method′s robustness and high-throughput capabilities make it ideal for ensuring food safety and compliance with regulatory standards (Khalikova et al., 2014).

Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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S Fan et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 30(12), 2093-2101 (2013-10-22)
A liquid chromatography-linear ion-trap spectrometry (LC-MS³) method using β-receptor molecular-imprinted polymer (MIP) solid-phase extraction (SPE) as clean-up was developed to determine simultaneously and confirmatively residues of 25 β₂-agonists and 21 β-blockers in urine samples. Urine samples were subjected to enzymatic
Michael T Furlong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 926, 36-41 (2013-04-02)
Clopidogrel is prescribed for the treatment of Acute Coronary Syndrome and recent myocardial infarction, recent stroke, or established peripheral arterial disease. A sensitive and reliable high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay was developed and validated to enable reliable
Hirotaka Kushida et al.
Biomedical chromatography : BMC, 27(12), 1647-1656 (2013-07-03)
Uncaria Hook (UH) alkaloids are involved in the beneficial effects of Yokukansan. However, the pharmacokinetics of UH alkaloids after oral administration of Yokukansan has not yet been sufficiently investigated. Therefore, we developed and validated a sensitive and specific high-performance liquid
Fan Sai et al.
Journal of agricultural and food chemistry, 60(8), 1898-1905 (2012-02-15)
A sensitive method has been developed for the simultaneous determination of residues of 25 β₂-agonists and 23 β-blockers in animal foods by high-performance liquid chromatography coupled with linear ion trap mass spectrometry (HPLC-LIT-MS). This method is based on a new
Erzsébet Oláh et al.
Journal of chromatography. A, 1217(23), 3642-3653 (2010-04-23)
Today sub-2 microm packed columns are very popular to conduct fast chromatographic separations. The mass-transfer resistance depends on the particle size but some practical limits exist not to reach the theoretically expected plate height and mass-transfer resistance. Another approach applies

Artikel

Improve your separation of basic compounds with our Ascentis® Express RP-Amide HPLC columns from the Supelco® portfolio.

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