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Dokumente

T3126

Sigma-Aldrich

D-α-Tocopherolsuccinat

semisynthetic, 1210 IU/g

Synonym(e):

Vitamin-E-succinat

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About This Item

Empirische Formel (Hill-System):
C33H54O5
CAS-Nummer:
4345-03-3
Molekulargewicht:
530.78
Beilstein:
4038233
EG-Nummer:
224-403-8
MDL-Nummer:
MFCD00072055
UNSPSC-Code:
12352205
eCl@ss:
34058016
PubChem Substanz-ID:
24900107
NACRES:
NA.28

Biologische Quelle

semisynthetic

Qualitätsniveau

200

Form

powder

Spezifische Aktivität

1210 IU/g

Farbe

white to yellow

Lagertemp.

room temp

SMILES String

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

InChI

1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1

InChIKey

IELOKBJPULMYRW-NJQVLOCASA-N

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Allgemeine Beschreibung

α-Tocopherol succinate is a fat soluble vitamin. α-Tocopherol is a form of vitamin E, which can be obtained through dietary sources. RRR-α-tocopherol is a natural form of α-Tocopherol.

Anwendung

D-α-Tocopherol succinate has been used:
  • to as a dietary supplement to study its immunomodulatory effects in chicks
  • as a dietary supplement in pregnant women to evaluate its effects on arsenic exposure
  • as an antioxidant to investigate concurrent pathways of cell death due to acute exercise

Biochem./physiol. Wirkung

α-Tocopherol is also called as a radical-chain breaker due to its anti-oxidant property.
Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. α-Tocopherol succinate is used along the α-Tocopherol acetate, α-Tocopherol nicotinate and other esterified forms as a vitamin E supplement with similar but differential activities.

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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DL-α-Tocopherolacetat ≥96% (HPLC)

Sigma-Aldrich

T3376

DL-α-Tocopherolacetat

α-Tocopherol ≥95.5%

Sigma-Aldrich

258024

α-Tocopherol

(±)-α-Tocopherol synthetic, ≥96% (HPLC)

Sigma-Aldrich

T3251

(±)-α-Tocopherol

DL-α-Tocopherol methoxypolyethylene glycol succinate

Sigma-Aldrich

763896

DL-α-Tocopherol methoxypolyethylene glycol succinate

(+)-δ-Tocopherol ≥90%

Sigma-Aldrich

T2028

(+)-δ-Tocopherol

Vitamin E-Acetat-(trimethyl-d9) 98 atom % D, 98% (CP)

Sigma-Aldrich

615366

Vitamin E-Acetat-(trimethyl-d9)

Vitamin E water-miscible 1 ml = 500 mg DL-a-tocopherol acetate for oral use, EMPROVE® ESSENTIAL, USP

SAFC

5.00862

Vitamin E

Effects of immunomodulatory nutrients on growth performance and immune-related gene expression in layer chicks challenged with lipopolysaccharide
Wils-Plotz EL and Klasing KC
Poultry Science, 96(3), 548-555 (2017)
J S Drukteinis et al.
Placenta, 26 Suppl A, S87-S95 (2005-04-20)
Maternal cigarette smoking is known to disrupt placental growth and function. The polyaromatic hydrocarbon benzo[a]pyrene (BaP) is a major toxicant in cigarette smoke that has been shown to alter placental cell function. This study compared the effects of the benzo[a]pyrene
Vijay K Singh et al.
International immunopharmacology, 9(12), 1423-1430 (2009-09-09)
Vitamin E is composed of a family of eight isomers known as tocols; consisting of four tocopherols and four tocotrienols that exist in four isomeric forms: alpha (alpha), beta (beta), gamma (gamma), and delta (delta). Earlier we have demonstrated the
Myocardial apoptosis and mesenchymal stem cells with acute exercise
Arisi MF, et al.
Physiological Reports, 5(11), e13297-e13297 (2017)
Wenbin Zhu et al.
PloS one, 9(3), e92992-e92992 (2014-03-26)
Benzo[a]pyrene (BaP), a well-known environmental carcinogen, promotes oxidative stress and DNA damage. Curcumin and vitamin E (VE) have potent antioxidative activity that protects cells from oxidative stress and cellular damage. The objectives of the present study were to investigate the
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