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P0275

Sigma-Aldrich

Poly(Glu, Tyr) Natriumsalz

greener alternative

Glu:Tyr (4:1), mol wt 20,000-50,000

Synonym(e):

Poly-(L-glutaminsäure-L-tyrosin) Natriumsalz

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About This Item

CAS-Nummer:
97105-00-5
MDL-Nummer:
MFCD00148022
UNSPSC-Code:
12352209
NACRES:
NA.26

Form

powder

Qualitätsniveau

200

Zufuhrverhältnis

Glu:Tyr (4:1)

Mol-Gew.

20,000-50,000

Grünere Alternativprodukt-Bewertung

old score: 48
new score: 45
Find out more about DOZN™ Scoring

Grünere Alternativprodukt-Eigenschaften

Safer Solvents and Auxiliaries
Design for Energy Efficiency
Reduce Derivatives
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Farbe

white to off-white

Grünere Alternativprodukt-Kategorie

, Re-engineered

Lagertemp.

−20°C

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Verwandte Kategorien

Allgemeine Beschreibung

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Safer Solvents and Auxiliaries”, “Enhanced Energy Efficiency” and “Reduced Derivative”. Click here to view its DOZN scorecard.

Anwendung

Poly(Glu, Tyr) sodium salt has been used as a substrate for
  • janus kinase 3 (JAK3) in enzyme linked immunosorbent assay (ELISA)-based assay
  • proto-oncogene tyrosine-protein kinase (Src) and zeta chain of T cell receptor associated protein kinase 70 (Zap70)
  • in in vitro tyrosine kinase assay

Biochem./physiol. Wirkung

Poly(glu, tyr) sodium salt is a polyamino acid with applications in cancer research.

Hinweis zur Analyse

Molecular weight based on viscosity. Also assayed by MALLS.

Sonstige Hinweise

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

A simple and robust automated kinase profiling platform using luminescent ADP accumulation technology
Larson B, et al.
Assay and Drug Development Technologies, 7(6), 573-584 (2009)
Jiaye Guo et al.
Biochemistry, 57(32), 4934-4951 (2018-07-06)
Human epidermal growth factor receptor 2 (HER2) is a validated breast cancer drug target for small molecule inhibitors that target the ATP-binding pocket of the kinase domain. In this work, a large-scale virtual screen was performed to a novel homology
Identification of Chinese Herbal Compounds with Potential as JAK3 Inhibitors
Su D, et al.
Evidence-Based Complementary and Alternative Medicine : ECAM (2019)
Dimerization of the Pragmin pseudo-kinase regulates protein tyrosine phosphorylation
Lecointre C, et al.
Structure, 26(4), 545-554 (2018)
C J Bruns et al.
Cancer research, 60(11), 2926-2935 (2000-06-13)
We determined whether down-regulation of the epidermal growth factor-receptor (EGF-R) signaling pathway by oral administration of a novel EGF-R tyrosine kinase inhibitor (PKI166) alone or in combination with gemcitabine (administered i.p.) can inhibit growth and metastasis of human pancreatic carcinoma

Artikel

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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