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Merck

O1257

Sigma-Aldrich

Oleic Acid-Water Soluble

powder, BioReagent, suitable for cell culture

Synonym(e):

Oleic Acid–Cyclodextrin Complex

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

MDL-Nummer:
UNSPSC-Code:
12352211
PubChem Substanz-ID:
NACRES:
NA.75

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Produktlinie

BioReagent

Form

powder

Zusammensetzung

Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)

Methode(n)

cell culture | mammalian: suitable

Löslichkeit

H2O: 50 mg/mL, clear to slightly hazy

Lagertemp.

−20°C

SMILES String

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChIKey

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

Angaben zum Gen

Anwendung

Oleic Acid-Water Soluble has been used:
  • to prepare the FFAs (free fatty acids) mixture for cell treatment
  • to investigate its effect on the solute carrier family 2 member 4 (SLC2A4)/GLUT4 expression in L6 muscle cells and as potential transcriptional regulators
  • in the preparation of fatting media for the induction of in vitro steatosis in primary human hepatocytes

Sonstige Hinweise

Methyl-β-cylodextran binding improves the solubility and delivery of Oleic acid in culture media.

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Preisangaben

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Analysenzertifikate (COA)

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Sigma-Aldrich

27728

Oleinsäure

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Natriumpalmitat ≥98.5%

Sigma-Aldrich

P9767

Natriumpalmitat

Oleic and linoleic fatty acids downregulate Slc2a4/GLUT4 expression via NFKB and SREBP1 in skeletal muscle cells
Poletto A C, et al.
Molecular and Cellular Endocrinology, 401(12), 65-72 (2015)
A20 attenuates FFAs-induced lipid accumulation in nonalcoholic steatohepatitis
Ai L, et al.
International Journal of Biological Sciences, 11(12), 1436-1436 (2015)
Takashi Okumura et al.
Oncotarget, 8(11), 18280-18295 (2017-04-15)
Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and metastasis of
An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells
Boteon YL, et al.
PLoS ONE, 13(7), e0201419-e0201419 (2018)
Katerina Brychtova et al.
Bioorganic & medicinal chemistry, 18(24), 8556-8565 (2010-11-09)
Skin penetration enhancers are used in the formulation of transdermal delivery systems for drugs that are otherwise not sufficiently skin-permeable. We generated two series of esters by multi-step synthesis with substituted 6-aminohexanoic acid as potential transdermal penetration enhancers by multi-step

Artikel

Fatty acids of the n-3, n-6 and n-9 families are important supplements for cell culture systems. They are important in cell culture systems used to biomanufacture heterologous proteins, such as monoclonal antibodies.

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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