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M1890

Sigma-Aldrich

rac-Glycerin-1-Myristat

≥99%

Synonym(e):

DL-α-Myristin, rac.-1-Myristoylglycerin

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About This Item

Lineare Formel:
H3C(CH2)12COOCH2CH(OH)CH2OH
CAS-Nummer:
589-68-4
Molekulargewicht:
302.45
Beilstein:
1727502
MDL-Nummer:
MFCD00046760
UNSPSC-Code:
12352211
PubChem Substanz-ID:
24896704
NACRES:
NA.25

Biologische Quelle

synthetic (organic)

Qualitätsniveau

200

Assay

≥99%

Form

powder

Funktionelle Gruppe

ester
hydroxyl

Lipid-Typ

neutral glycerides

Versandbedingung

ambient

Lagertemp.

−20°C

SMILES String

CCCCCCCCCCCCCC(=O)OCC(O)CO

InChI

1S/C17H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)21-15-16(19)14-18/h16,18-19H,2-15H2,1H3

InChIKey

DCBSHORRWZKAKO-UHFFFAOYSA-N

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Allgemeine Beschreibung

rac-Glycerol 1-myristate is present in the saw palmetto palm and is less soluble in water.

Anwendung

rac-Glycerol 1-myristate has been used:
  • as a standard in liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry (LC–APCI-MS) studies
  • as a representative monoacylglycerol to test its matrix effects in gas chromatography-mass spectrometry (GC-MS) studies
  • to test its antifungal activity against Fusarium spp.

Rac-glycerol 1-myristate (glycerol α-monomyristate) is used in colloidal chemistry as a nonionic surfactant in the development of micelles.

Biochem./physiol. Wirkung

rac-Glycerol 1-myristate also elicits antifungal activity. It exhibits an anti-proliferative effect in HeLa cervical cancer cells when delivered as a polymeric nanoparticle-based conjugate.
rac-Glycerol 1-myristate, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Hayami et al.
Journal of colloid and interface science, 220(2), 374-379 (1999-12-23)
The interfacial tension of a hexane solution of 1-monolaurin against water was measured as a function of temperature and concentration under atmospheric pressure. The thermodynamic quantity changes associated with the adsorption of 1-monolaurin were evaluated and compared with those of
Lok Kumar Shrestha et al.
The journal of physical chemistry. B, 113(18), 6290-6298 (2009-04-11)
In this paper we present the study of reverse micellar aggregates formed by glycerol alpha-monomyristate (C(14)G(1)) in different organic solvents. We have investigated the structure (mainly shape and size) of the monomyristin reverse micelles depending on alkyl chain length of
Wakako Tsuzuki
Lipids, 42(7), 613-619 (2007-06-22)
To elucidate the absorption characteristics of dietary lipids in the human intestine, we investigated the cellular uptake of lipid metabolites using a differential monolayer of the Caco2 cells. As lipid metabolites, several free fatty acids and 2-monoacylglycerols, were formed a
M Suman et al.
Journal of chromatography. A, 1216(18), 3758-3766 (2009-03-17)
A new, reliable liquid chromatography/atmospheric-pressure chemical ionisation mass spectrometry (LC-APCI-MS) method was developed for the quantitative determination of food emulsifiers composed of mono- and diacylglycerols of fatty acids (E471 series) in complex food matrices. These additives are extremely interesting for
Sirirat Boondireke et al.
Colloids and surfaces. B, Biointerfaces, 176, 9-17 (2018-12-28)
The cytotoxicity of monomyristin (MM), a monoacylglycerol, was investigated against cervical cancer cells (HeLa) and two normal cells (Vero and endometrial epithelial cells). MM exhibited cytotoxicity specifically to HeLa cells and not against normal cells except at the highest investigated
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