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L3625

Sigma-Aldrich

α-Laktose Monohydrat

≥99% total lactose basis (GC)

Synonym(e):

β-D-Gal-(1→4)-α-D-Glc, 4-O-β-D-Galactopyranosyl-α-D-glucose, Milchzucker

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About This Item

Empirische Formel (Hill-System):
C12H22O11 · H2O
CAS-Nummer:
5989-81-1
Molekulargewicht:
360.31
MDL-Nummer:
MFCD00150747
UNSPSC-Code:
12352201
PubChem Substanz-ID:
57654326
NACRES:
NA.25

Biologische Quelle

bovine milk

Qualitätsniveau

200

Assay

≥99% total lactose basis (GC)

Form

powder

Verunreinigungen

≤0.05% Glucose
≤4% β-lactose

Farbe

white to off-white

mp (Schmelzpunkt)

219  °C ((426 °F ))

Löslichkeit

water: 100 mg/mL, clear, colorless

Lagertemp.

room temp

SMILES String

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1

InChIKey

WSVLPVUVIUVCRA-KPKNDVKVSA-N

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Verwandte Kategorien

Anwendung


  • Crystal size, a key character of lactose crystallization affecting microstructure, surface chemistry and reconstitution of milk powder.: This study uses alpha-lactose monohydrate as a standard to investigate how crystal size affects the physical properties of milk powder, which is crucial for optimizing production processes in the dairy industry (Qi X et al., 2024).

  • Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with alpha-Lactose Monohydrate.: Explores the critical role of alpha-lactose monohydrate, as an excipient together with terbutaline sulfate in optimizing particle interactions for enhanced performance of inhalable therapeutics (Ma CY et al., 2023).

  • Terahertz time-domain spectroscopy for the investigation of tablets prepared from roller compacted granules.: This research utilizes alpha-lactose monohydrate to examine the properties of pharmaceutical tablets, offering insights into material characteristics that affect drug delivery systems (Anuschek M et al., 2023).

Biochem./physiol. Wirkung

Lactose is a dissacharide formed by the condensation of one galactose and one glucose molecule. Lactose is the major sugar in the milk of most species, typically present between 2-8%.
alpha-Lactose is the primary sugar present in milk and the main energy source to a newborn mammalian through its mother′s milk. It is digested by the intestinal lactase (EC 3.2.1.108), an enzyme expressed in newborns. The enzyme′s activity declines following weaning which can lead to lactose intolerance in adult mammals.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Lactose, wasserfrei European Pharmacopoeia (EP) Reference Standard

A1206000

Lactose, wasserfrei

Lactose Monohydrat United States Pharmacopeia (USP) Reference Standard

USP

1356701

Lactose Monohydrat

Lactose Monohydrat European Pharmacopoeia (EP) Reference Standard

Y0001750

Lactose Monohydrat

Sigma-Aldrich

Sigma-Aldrich

L7634

α-Laktose-Agarose

Lactose monohydrate milk sugar, suitable for microbiology

Millipore

1.07657

Lactose monohydrate

Lactose, wasserfrei Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1025

Lactose, wasserfrei

Laktosemonohydrat powder, EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, NF

SAFC

1.07656

Laktosemonohydrat

Gwenola Le Dréan et al.
Nutrients, 11(9) (2019-08-24)
Oligosaccharides (OS) are commonly added to infant formulas, however, their physiological impact, particularly on adult health programming, is poorly described. In adult animals, OS modify microbiota and stimulate colonic fermentation and enteroendocrine cell (EEC) activity. Since neonatal changes in microbiota
Johannes Gursch et al.
Journal of pharmaceutical sciences, 104(10), 3481-3489 (2015-07-07)
Over the last years, continuous manufacturing has created significant interest in the pharmaceutical industry. Continuous filtration at low flow rates and high solid loadings poses, however, a significant challenge. A commercially available, continuously operating, dynamic cross-flow filtration device (CFF) is
Sha Liu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 132-142 (2015-07-30)
Co-administration of an inhaled corticosteroid and long acting beta agonist for chronic obstructive pulmonary disease has reduced mortality compared to either drug alone. This combination reduces exacerbations, hospitalization, emergency department visits and health care costs. A novel fixed-dose combination of

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