Direkt zum Inhalt
Merck

GE11-0034-93

HiTrap® MabSelect SuRe

Cytiva 11-0034-93, pack of 5 × 1 mL

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
23151816
NACRES:
NA.56

ligand

alkali-stabilized protein A-derived (E. coli)

Verpackung

pack of 5 × 1 mL

Hersteller/Markenname

Cytiva 11-0034-93

Lagerbedingungen

(20% Ehtanol)
(20% Ethanol)

Parameter

flow rate
<4 ml/min flow rate
42 psi

Bettgröße

7 mm × 25 mm

Bettvolumen

1 mL

Säule ID

7 mm

Matrix

highly cross-linked agarose

Durchschnittliche Teilgröße

85 μm (d₅₀v is the median particle size of the cumulative volume distribution)

cleaning

2-13.7

working range

3-12

Kapazität

≥30 mg binding capacity (humanlgG/ml at 2.4 min residence time)

Eignung

suitable for bioprocess medium

Lagertemp.

2-8°C

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Verwandte Kategorien

Allgemeine Beschreibung

Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.
HiTrap® MabSelect SuRe columns are prepacked with MabSelect SuRe, a BioProcess medium for purification of monoclonal antibodies from large sample volumes. The novel alkali-tolerant recombinant Protein A ligand allow cleaning-in-place (CIP).

HiTrap® MabSelect columns are prepacked with MabSelect a bioprocess medium for capuring of Mabs from large sample volumes.
pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.

Leistungsmerkmale und Vorteile

  • Withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH.
  • Novel ligand design gives enhanced protease resistance resulting in lower ligand leakage.
  • Oriented coupling of recombinant Protein A to the matrix via an engineered C-terminal cysteine enhances IgG binding capacity.
  • Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification.
  • Prepacked HiTrap® columns for process development, screening of purification conditions, and small-scale purification of Mabs.

Lagerung und Haltbarkeit

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Hinweis zur Analyse

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Sonstige Hinweise

1)The pressure over the packed bed varies depending on a range of parameters such as the characteristics of the chromatography medium and the column tubing used.

Rechtliche Hinweise

Free MabSelect SuRe Ligand
"MabSelect SuRe Ligand Restricted License" and "Cys-rProtein A Ligand Restricted License" are protected by the following patents and equivalent patents and patent applications in other countries: US 6,399,750 and EP 1123389. A free, non-transferable limited license to use this product for internal analytical purposes only accompanies the purchase of the product from a Cytiva company and its licensed distributors. Any other use will require a separate license from a Cytiva company.
HiTrap is a registered trademark of Cytiva
MabSelect is a trademark of Cytiva
MabSelect SuRe is a trademark of Cytiva
SuRe is a trademark of Cytiva

Piktogramme

Flame

Signalwort

Warning

H-Sätze


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 7

1 of 7

HiScreen&#8482; MabSelect SuRe&#8482; LX Cytiva 17-5474-15

GE17-5474-15

HiScreen MabSelect SuRe LX

HiTrap&#174; Q Fast Flow Cytiva 17-5053-01, pack of 5 × 1&#160;mL

GE17-5053-01

HiTrap® Q Fast Flow

MabSelect&#8482; Cytiva 17-5199-01, pack of 25&#160;mL

GE17-5199-01

MabSelect

MabSelect&#8482; SuRe&#8482; Cytiva 17-5438-02, pack of 200&#160;mL

GE17-5438-02

MabSelect SuRe

MabSelect SuRe&#8482; LX Cytiva 17-5474-02, pack of 200&#160;mL

GE17-5474-02

MabSelect SuRe LX

HisTrap&#8482; Excel Cytiva 17-3712-06, pack of 5 × 5&#160;mL

GE17-3712-06

HisTrap Excel

Artikel

Desalting at laboratory scale is a well-proven, simple, and fast method that will rapidly remove low molecular weight contaminants at the same time as transferring the sample into the desired buffer in a single step.

Protokolle

This page shows how to separate IgG antibodies by affinity chromatography using MabSelect Sure from Cytiva.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.