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G1001

Sigma-Aldrich

D-Glutaminsäure

≥99% (TLC)

Synonym(e):

(R)-2-Amino-glutarsäure, (R)-2-Aminopentandisäure, D-Glu, R-(−)-1-Aminopropan-1,3-dicarbonsäure

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About This Item

Lineare Formel:
HO2CCH2CH2CH(NH2)CO2H
CAS-Nummer:
6893-26-1
Molekulargewicht:
147.13
Beilstein:
1723800
EG-Nummer:
230-000-8
MDL-Nummer:
MFCD00063112
UNSPSC-Code:
12352209
PubChem Substanz-ID:
24895031
NACRES:
NA.32

Qualitätsniveau

200

Assay

≥99% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

white to off-white

mp (Schmelzpunkt)

200-202 °C (subl.) (lit.)

SMILES String

N[C@H](CCC(O)=O)C(O)=O

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1

InChIKey

WHUUTDBJXJRKMK-GSVOUGTGSA-N

Angaben zum Gen

human ... CCR2(1231)

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Allgemeine Beschreibung

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.

Anwendung

D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.

Biochem./physiol. Wirkung

unnatürliches Glutaminsäure-Isomer

Anwendung

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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L-Glutaminsäure from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%

Sigma-Aldrich

G8415

L-Glutaminsäure

D-Alanin ≥98% (HPLC)

Sigma-Aldrich

A7377

D-Alanin

D-Tyrosin ReagentPlus®, 99%

Sigma-Aldrich

855456

D-Tyrosin

P Doublet et al.
Journal of bacteriology, 174(18), 5772-5779 (1992-09-01)
The murI gene of Escherichia coli, whose inactivation results in the inability to form colonies in the absence of D-glutamic acid, was identified in the 90-min region of the chromosome. The complementation of an auxotrophic E. coli B/r strain by
Katie L Whalen et al.
Molecular informatics, 30(5), 459-471 (2011-07-09)
Existing techniques which attempt to predict the affinity of protein-ligand interactions have demonstrated a direct relationship between computational cost and prediction accuracy. We present here the first application of a hybrid ensemble docking and steered molecular dynamics scheme (with a
Matthew Volgraf et al.
Nature chemical biology, 2(1), 47-52 (2006-01-13)
The precise regulation of protein activity is fundamental to life. The allosteric control of an active site by a remote regulatory binding site is a mechanism of regulation found across protein classes, from enzymes to motors to signaling proteins. We
H Persson et al.
Molecular and cellular biology, 10(9), 4701-4711 (1990-09-01)
The gene encoding glutamic acid decarboxylase (GAD), the key enzyme in the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid, is shown to be expressed in the testis of several different species. Nucleotide sequence analysis of a cDNA clone isolated from
Jia Luo et al.
Science (New York, N.Y.), 298(5592), 425-429 (2002-10-12)
The motor abnormalities of Parkinson's disease (PD) are caused by alterations in basal ganglia network activity, including disinhibition of the subthalamic nucleus (STN), and excessive activity of the major output nuclei. Using adeno-associated viral vector-mediated somatic cell gene transfer, we
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Chromatograms

application for HPLC

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