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E9145

Sigma-Aldrich

Estrone 3-sulfate potassium salt

≥98%

Synonym(e):

1,3,5(10)-Estratrien-17-one 3-sulfate

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About This Item

Lineare Formel:
C18H21O5SK
CAS-Nummer:
1240-04-6
Molekulargewicht:
388.52
EG-Nummer:
214-985-1
MDL-Nummer:
MFCD00056410
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24894691
NACRES:
NA.77

Qualitätsniveau

200

Assay

≥98%

Form

powder

Enthält

~35% Tris as stabilizer

Farbe

off-white to light tan

Löslichkeit

methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow

Versandbedingung

ambient

Lagertemp.

−20°C

SMILES String

[K].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24

InChI

1S/C18H22O5S.K.H/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);;/t14-,15-,16+,18+;;/m1../s1

InChIKey

XFQXTMKDDYWSBS-DLEHHZMWSA-N

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Biochem./physiol. Wirkung

The most abundant estrogen in adult human circulation. Conversion to estradiol requires steroid sulfatase activity. This activity was used to evaluate freshly resected bone fragments against cultured osteoblasts and osteosearcoma cells as models for studying human bone metabolism.

Verpackung

Packungsgrösse basiert auf dem Steroidgehalt

Piktogramme

Exclamation markHealth hazard
GHS07,GHS08

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Repr. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Estron ≥99%

Sigma-Aldrich

E9750

Estron

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Sigma-Aldrich

344847

Fumitremorgin C, Aspergillus. fumigatus

β-Estradiol 3-(β-D-glucuronide) sodium salt

Sigma-Aldrich

E2127

β-Estradiol 3-(β-D-glucuronide) sodium salt

4-Amino-hippursäure ≥99%

Sigma-Aldrich

A1422

4-Amino-hippursäure

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Sigma-Aldrich

E8126

Equilin

Estriol ≥97%

Sigma-Aldrich

E1253

Estriol

Dehydroepiandrosteron-3-Sulfat (DHEAS) Natriumsalz -Lösung 1.0 mg/mL in methanol (as free sulfate), ampule of 1 mL, certified reference material, Cerilliant®

Supelco

D-065

Dehydroepiandrosteron-3-Sulfat (DHEAS) Natriumsalz -Lösung

Digoxin analytical standard

Supelco

D6003

Digoxin

Maria Karlgren et al.
Journal of medicinal chemistry, 55(10), 4740-4763 (2012-05-01)
The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug-drug interactions. Predicting potential interactions with OATPs is, therefore, of value. Here, we developed in vitro and in silico models
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 47(4), 774-780 (2012-09-18)
Previously, the steroid hormone progesterone has been demonstrated to stimulate OATP2B1-mediated transport of estrone-3-sulphate (E(1)S), dehydroepiandrosterone sulphate (DHEAS) and pregnenolone sulphate (PS), which may influence the uptake of precursor molecules for steroid hormone synthesis. However, it is unclear whether OATP2B1
L M M C Sousa et al.
Placenta, 33(10), 788-794 (2012-07-31)
Our objectives were to investigate the possible role of VEGFA in bovine placenta steroid synthesis and to determine whether cloned derived placental cells present similar responses as non-cloned ones. Placental cells from cloned (term) and non-cloned (days 90, 150, 210
Elizabeth J Folkerd et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(24), 2977-2980 (2012-07-18)
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Levels of endogenous estrogen and SHBG are associated with risk of breast cancer among women who have never used hormone replacement therapy (HRT). We investigated these associations in both never and baseline users of HRT. A nested case-control study was
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