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D3676

Sigma-Aldrich

10-Deacetylbaccatin III from Taxus baccata

≥95% (HPLC)

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About This Item

Empirische Formel (Hill-System):
C29H36O10
CAS-Nummer:
32981-86-5
Molekulargewicht:
544.59
MDL-Nummer:
MFCD00132913
UNSPSC-Code:
51101500
PubChem Substanz-ID:
24893778
NACRES:
NA.85

Biologische Quelle

Taxus baccata

Qualitätsniveau

200

Assay

≥95% (HPLC)

Form

solid

Mol-Gew.

544.59 g/mol

Farbe

white

Löslichkeit

methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH)

Wirkungsspektrum von Antibiotika

neoplastics

Wirkungsweise

DNA synthesis | interferes

Lagertemp.

2-8°C

SMILES String

[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@@H](O)C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C

InChI

1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1

InChIKey

YWLXLRUDGLRYDR-ZHPRIASZSA-N

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Verwandte Kategorien

Anwendung

10-Deacetylbaccatin III is used as a chemical intermediate in the preparation of the anti-cancer drug paclitaxel (Taxol). It is used to study the taxol biosynthetic pathway.

Biochem./physiol. Wirkung

10-Deacetylbaccine III is the fifth intermediate of paclitaxel biosynthesis. The biosynthetic pathway consists of approximately 20 enzymatic steps but is not fully elucidated.

Piktogramme

Exclamation markHealth hazard
GHS07,GHS08

Signalwort

Danger

Gefahreneinstufungen

Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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