C4407
Human Collagen Type III
from human placenta, powder, suitable for cell culture
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Alle Fotos(2)
About This Item
Empfohlene Produkte
product name
Kollagen aus menschlicher Placenta, Bornstein and Traub Type III (Sigma Type X), powder
Biologische Quelle
human placenta
Qualitätsniveau
Assay
≥90% (GE)
Form
powder
Methode(n)
cell culture | mammalian: suitable
Verunreinigungen
HIV, hepatitis B and hepatitis C, none detected
Löslichkeit
aqueous acid: soluble
UniProt-Hinterlegungsnummer
Lagertemp.
2-8°C
Angaben zum Gen
human ... COL3A1(1300)
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Anwendung
Collagen from human placenta has been used to assess the bioelectric effects of quinine on airway epithelial cells, to study the selective toxicity of engineered lentvirus lytic peptides and in a particle aggregation assay for the rapid detection of fibronectin, fibrinogen and collagen receptors on Staphylococcus aureus. It has also been used in a magnesium-dependent, collagen-binding assay during characterization of human lung tumor-associated antigens.
Komponenten
All collagen molecules are composed of three polypeptide chains arranged in a triple helical conformation, with a primary structure that is mostly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceding the glycine residue.
Vorsicht
This product should be stored at 2-8 °C and will retain activity in these conditions for 2 years.
Angaben zur Herstellung
This product was prepared by a modification of the pepsin extraction and salt fractionation method of Hill, R.J. and Harper, E., Anal. Biochem., 141 (1984). It is a lyophilized powder that can be reconstituted in sterile .5 M acetic acid, PBS or water at 1 mg/mL. A PBS solution will be stable for at least one year at -20°C.
Hinweis zur Analyse
An SDS polyacrylamide gel electrophoresis test run under reducing conditions consistent with basement membrane collagen yields three major bands.
Sonstige Hinweise
Kollagen wird in eine Reihe an strukturell und genetisch verschiedenen Typen unterteilt. Wir nutzen die Nomenklatur, die von Bornstein und Traub vorgeschlagen wurde. Achten Sie darauf, dass Sie die Typenbezeichnungen von Sigma nicht mit anerkannten Typenklassifizierungen von Kollagen verwechseln.
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
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