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A8980

Sigma-Aldrich

Acarbose

≥95% (HPLC)

Synonym(e):

4",6"-Didesoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-cyclohexenylamino)-maltotriose

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About This Item

Empirische Formel (Hill-System):
C25H43NO18
CAS-Nummer:
56180-94-0
Molekulargewicht:
645.60
EG-Nummer:
260-030-7
MDL-Nummer:
MFCD00869592
UNSPSC-Code:
12352201
PubChem Substanz-ID:
329771024
NACRES:
NA.25

Biologische Quelle

bacterial (Actinoplanes)

Qualitätsniveau

200

Assay

≥95% (HPLC)

Form

powder

Verunreinigungen

<9.4% water (Karl Fischer)

Farbe

white to off-white

Löslichkeit

H2O (CO2 free): 50 mg/mL, clear, colorless

Lagertemp.

room temp

SMILES String

C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O

InChI

1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1

InChIKey

XUFXOAAUWZOOIT-SXARVLRPSA-N

Angaben zum Gen

human ... AMY2A(279) , MGAM(8972)

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Verwandte Kategorien

Anwendung

Acarbose, a derivitized maltotriose antidiabetic drug, is a reversible α-glucosidase inhibitor used in medical studies to control the effects of Type II diabetes. Acarbose is often used as a reference to which other α-glucosidase inhibitors are compared.

Biochem./physiol. Wirkung

Modifiziertes Tetrasaccharid, das als reversibler α-Glucosidase-Inhibitor wirkt.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Sigma-Aldrich

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USP

USP

1000532

Acarbose-Systemeignungsmischung

&#945;-Glucosidase from Bacillus stearothermophilus lyophilized powder, &#8805;50&#160;units/mg protein

Sigma-Aldrich

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&#945;-Glucosidase-Assay suitable for activity assay, kit of 1 (5 components)

Roche

11742027001

α-Glucosidase-Assay

Avenacoside A &#8805;95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00251

Avenacoside A

3,5-Dinitrosalicylsäure used in colorimetric determination of reducing sugars

Sigma-Aldrich

D0550

3,5-Dinitrosalicylsäure

Ranee Singh et al.
Journal of feline medicine and surgery, 17(10), 848-857 (2014-10-26)
Feeding a low carbohydrate diet is recommended for diabetic cats; however, some cats may require diets containing moderate-to-high carbohydrate and may benefit from the use of therapeutic agents to improve glycemic control. The aim of the study was to determine
Muhammad Jihad Sandikapura et al.
Pakistan journal of pharmaceutical sciences, 31(2(Suppl.)), 623-635 (2018-04-08)
The study was aimed to perform aqueous extraction of two plants using different extraction methods, and evaluate their antioxidant and antidiabetic potential. Plant materials were extracted by maceration, soxhlet, sonication and fresh juice methods to produce aqueous extracts. In vitro
Alessandro Leone et al.
Nutrients, 10(10) (2018-10-17)
The hypoglycemic effect in humans of Moringa oleifera (MO) leaf powder has, to date, been poorly investigated. We assessed the chemical composition of MO leaf powder produced at Saharawi refugee camps, its in vitro ability to inhibit α-amylase activity, and
Ashley S Boath et al.
Food chemistry, 135(3), 929-936 (2012-09-08)
Polyphenol-rich extracts from certain berries inhibited α-glucosidase activity in vitro. The two most effective berry extracts, from black currant and rowanberry, inhibited α-glucosidase with IC(50) values respectively of 20 and 30μg GAE/ml and were as effective as the pharmaceutical inhibitor
Henriëtte J Rozeboom et al.
The Journal of biological chemistry, 288(37), 26764-26774 (2013-08-02)
α-1,4-Glucan lyase (EC 4.2.2.13) from the red seaweed Gracilariopsis lemaneiformis cleaves α-1,4-glucosidic linkages in glycogen, starch, and malto-oligosaccharides, yielding the keto-monosaccharide 1,5-anhydro-D-fructose. The enzyme belongs to glycoside hydrolase family 31 (GH31) but degrades starch via an elimination reaction instead of
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