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Y0001425

Nicotine ditartrate Dihydrat

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(−)-Nikotin -hydrogen-tartrat (Salz) Dihydrat

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About This Item

Empirische Formel (Hill-System):
C10H14N2 · 2C4H6O6 · 2H2O
CAS-Nummer:
Molekulargewicht:
498.44
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

nicotine

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

InChI

1S/C17H15ClN2O3/c1-9(2)16(22)19-11-4-5-14(21)12(8-11)17-20-13-7-10(18)3-6-15(13)23-17/h3-9,20H,1-2H3,(H,19,22)/b17-12-

InChIKey

YGMGVHYZWYRTJJ-ATVHPVEESA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Nicotine ditartrate dihydrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 1 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 1

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Sigma-Aldrich

N0267

(±)-Nikotin

(-)-Nicotine for synthesis

Sigma-Aldrich

8.20877

(-)-Nicotine

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Supelco

N5511

(−)-Nikotin -Lösung

(−)-Nikotin PESTANAL®, analytical standard

Supelco

36733

(−)-Nikotin

Alexander Duncan et al.
Nature, 574(7778), 372-377 (2019-10-18)
Diabetes is far more prevalent in smokers than non-smokers, but the underlying mechanisms of vulnerability are unknown. Here we show that the diabetes-associated gene Tcf7l2 is densely expressed in the medial habenula (mHb) region of the rodent brain, where it
Wouter Goutier et al.
Addiction biology, 20(2), 248-258 (2013-11-21)
The present study focused on the evaluation of behavioral sensitization and cross-sensitization induced by nicotine and varenicline in rats. Furthermore, it examined the influence of varenicline, a partial alpha4beta2 nicotinic receptor agonist, on nicotine-induced sensitization. To assess the development of

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