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Y0001048

Levodropropizin Unreinheit C

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(±)-Glycidol, (±)-Oxiran-2-methanol, 2,3-Epoxy-1-propanol, Glyceringlycide

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About This Item

Empirische Formel (Hill-System):
C3H6O2
CAS-Nummer:
556-52-5
Molekulargewicht:
74.08
Beilstein:
383562
MDL-Nummer:
MFCD00005147
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329831237
NACRES:
NA.24

Qualität

pharmaceutical primary standard

Dampfdichte

2.15 (vs air)

Dampfdruck

0.9 mmHg ( 25 °C)

API-Familie

levodropropizine

Selbstzündungstemp.

780 °F

Hersteller/Markenname

EDQM

Brechungsindex

n20/D 1.433 (lit.)

bp

61-62 °C/15 mmHg (lit.)

Dichte

1.117 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

−20°C

SMILES String

OCC1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2

InChIKey

CTKINSOISVBQLD-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Levodropropizine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

WGK

WGK 3

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 769, 1-6 (2014-10-26)
The in vivo comet assay has been used for the evaluation of DNA damage and repair in various tissues of rodents. However, it can give false-positive results due to non-specific DNA damage associated with cell death. In this study, we
Hirotoshi Akane et al.
Toxicology and applied pharmacology, 279(2), 150-162 (2014-06-11)
We previously found that the 28-day oral toxicity study of glycidol at 200mg/kg/day in rats resulted in axonopathy in both the central and peripheral nervous systems and aberrations in the late-stage of hippocampal neurogenesis targeting the process of neurite extension.
Nadiya Bakhiya et al.
Molecular nutrition & food research, 55(4), 509-521 (2011-02-26)
Fatty acid esters of 3-chloropropane-1,2-diol (3-MCPD) and glycidol are a newly identified class of food process contaminants. They are widespread in refined vegetable oils and fats and have been detected in vegetable fat-containing products, including infant formulas. There are no
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