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T1300000

Thioridazin -hydrochlorid

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

10-[2-(1-Methyl-2-piperidyl)-ethyl]-2-(methylthio)-10H-phenothiazin -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C21H26N2S2 · HCl
CAS-Nummer:
130-61-0
Molekulargewicht:
407.04
MDL-Nummer:
MFCD00012655
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329826662
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

thioridazine

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Cl.CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1

InChI

1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H

InChIKey

NZFNXWQNBYZDAQ-UHFFFAOYSA-N

Angaben zum Gen

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Thioridazine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

WGK

WGK 3

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Amandeep Singh et al.
Tuberculosis (Edinburgh, Scotland), 94(6), 695-700 (2014-10-12)
Thioridazine, a potent phenothiazine compound was evaluated for its chemotherapeutic efficacy against experiment model of tuberculosis. Thioridazine potentiated the activities of both isoniazid and rifampicin (>1 log CFU reduction) against the in vitro latent Mycobacterium tuberculosis bacilli. Further, a murine
Jadel M Kratz et al.
Journal of chemical information and modeling, 54(10), 2887-2901 (2014-08-26)
The goal of this study was to design, experimentally validate, and apply a virtual screening workflow to identify novel hERG channel blockers. The hERG channel is an important antitarget in drug development since cardiotoxic risks remain as a major cause

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