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Merck

S7920

Sigma-Aldrich

Natriumfluorid

BioXtra, ≥99%

Synonym(e):

NaF, Natrium fluoride, Sodium monoflouride

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About This Item

Lineare Formel:
NaF
CAS-Nummer:
Molekulargewicht:
41.99
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352302
PubChem Substanz-ID:
NACRES:
NA.25

Dampfdruck

1.4 mmHg ( 0 °C)

Qualitätsniveau

Produktlinie

BioXtra

Assay

≥99%

Verunreinigungen

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp (Schmelzpunkt)

993 °C (lit.)

Löslichkeit

H2O: 1 M, clear, colorless

Anionenspuren

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%

Kationenspuren

Al: ≤0.001%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES String

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChIKey

PUZPDOWCWNUUKD-UHFFFAOYSA-M

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Anwendung

Sodium fluoride has been used:
  • as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
  • as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
  • as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Biochem./physiol. Wirkung

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.

Piktogramme

Skull and crossbones

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Zusätzliche Gefahrenhinweise

Lagerklassenschlüssel

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Analysenzertifikate (COA)

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Natriumfluorid ReagentPlus®, ≥99%

Sigma-Aldrich

S1504

Natriumfluorid

Natriumfluorid United States Pharmacopeia (USP) Reference Standard

USP

1614002

Natriumfluorid

Natriumfluorid extra pure, for table water

SAFC

1.72576

Natriumfluorid

Natriumfluorid puriss., meets analytical specification of Ph. Eur., BP, USP, 98.5-100.5% (calc. to the dried substance)

Sigma-Aldrich

01148

Natriumfluorid

Fluorid-Ionenlösung für ISE 0.1 M F-, analytical standard (for ion-selective electrodes)

Supelco

47072

Fluorid-Ionenlösung für ISE

Natriumfluorid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1408

Natriumfluorid

Fluoride-induced oxidative stress and apoptosis are involved in the reducing of oocytes development potential in mice
Wang HW, et al.
Chemosphere, 186, 911-918 (2017)
Effects of treatment with fluoride on bone mineral density and fracture risk-a meta-analysis
Vestergaard P, et al.
Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 19(3), 257-268 (2008)
Dental caries
Selwitz RH, et al.
Lancet, 369(9555), 51-59 (2007)
Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle
Rosner M, et al.
Nature Protocols, 8(3), 602-602 (2013)
18F-sodium fluoride positron emission tomography for molecular imaging of coronary atherosclerosis based on computed tomography analysis
Kitagawa T, et al.
Atherosclerosis, 263(3), 385-392 (2017)

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