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Dokumente

PHR1874

Atorvastatin-verwandte Verbindung I

Name: Atorvastatin-verwandte Verbindung I
Brand: SIAL

pharmaceutical secondary standard, certified reference material

Synonym(e):

tert-Butyl-(4R,6R)-6-[2-[2-(4-fluorphenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1-pyrrolyl]ethyl]-2,2-dimethyl-1,3-dioxan-4-acetat

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About This Item

Empirische Formel (Hill-System):

C₄₀H₄₇FN₂O₅

CAS-Nummer:

125971-95-1

Molekulargewicht:

654.81

MDL-Nummer:

MFCD04039904

UNSPSC-Code:

12352005

NACRES:

NA.24

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USP

1044593

Atorvastatin-verwandte Verbindung I

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PHR1046

Ethylenglycol

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to USP 1044593

API-Familie

atorvastatin

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 30 mg

mp (Schmelzpunkt)

144-148 °C (lit.)

Anwendung(en)

pharmaceutical

Format

neat

Lagertemp.

2-8°C

SMILES String

CC(C)c1c(C(=O)Nc2ccccc2)c(-c3ccccc3)c(-c4ccc(F)cc4)n1CC[C@@H]5C[C@H](CC(=O)OC(C)(C)C)OC(C)(C)O5

InChI

1S/C40H47FN2O5/c1-26(2)36-35(38(45)42-30-16-12-9-13-17-30)34(27-14-10-8-11-15-27)37(28-18-20-29(41)21-19-28)43(36)23-22-31-24-32(47-40(6,7)46-31)25-33(44)48-39(3,4)5/h8-21,26,31-32H,22-25H2,1-7H3,(H,42,45)/t31-,32-/m1/s1

InChIKey

NPPZOMYSGNZDKY-ROJLCIKYSA-N

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Allgemeine Beschreibung

This material is an impurity of atorvastatin. Atorvastatin is a synthetic HMG-CoA reductase inhibitor which lowers plasma cholesterol levels by inhibiting endogenous cholesterol synthesis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Atorvastatin may be used as a pharmaceutical reference standard for the determination of the analyte in drug dosage forms by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB1040 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

PHR1868

PHR2421

1,1-Dimethylethyl (4R-cis)-6-Aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Y0002315

Atorvastatin calcium, CRS, European Pharmacopoeia (EP) Reference Standard

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

LRAD0695

LRAB1040

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Atorvastatin associated liver disease

Clarke, AT and Mills, PR

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 38(10), 772-777 (2006)

An HPLC method for the determination of atorvastatin and its impurities in bulk drug and tablets

Erturk S, et al.

Journal of Pharmaceutical and Biomedical Analysis, 33(5), 1017-1023 (2003)

HPLC methods for the determination of simvastatin and atorvastatin

Novakova L, et al.

TrAC, Trends in Analytical Chemistry, 27(4), 352-367 (2008)

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Dokumente

Atorvastatin-verwandte Verbindung I

pharmaceutical secondary standard, certified reference material

About This Item

Empfohlene Produkte

Eigenschaften

Qualität

Qualitätsniveau

Agentur

API-Familie

Analysenzertifikat (CofA)

Verpackung

mp (Schmelzpunkt)

Anwendung(en)

Format

Lagertemp.

SMILES String

InChI

InChIKey

Verwandte Kategorien

Beschreibung

Allgemeine Beschreibung

Anwendung

Hinweis zur Analyse

Sonstige Hinweise

Fußnote

Verwandte Produkte

Ähnliches Produkt

Sicherheitshinweise

Lagerklassenschlüssel

WGK

Flammpunkt (°F)

Flammpunkt (°C)

Dokumentation

Analysenzertifikate (COA)

Besitzen Sie dieses Produkt bereits?

Peer-Reviewed-Artikel

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