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PHR1721

Supelco

Terazosin-Hydrochlorid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Terazosin -hydrochlorid Dihydrat, 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-[(tetrahydro-2-furanyl)-carbonyl]-piperazin -hydrochlorid Dihydrat

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About This Item

Empirische Formel (Hill-System):
C19H25N5O4 · HCl · 2H2O
CAS-Nummer:
70024-40-7
Molekulargewicht:
459.92
MDL-Nummer:
MFCD00941408
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823574
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to Ph. Eur. Y0000621
traceable to USP 1643452

API-Familie

terazosin

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 1 g

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

O.O.Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4

InChI

1S/C19H25N5O4.ClH.2H2O/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;;;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H;2*1H2

InChIKey

NZMOFYDMGFQZLS-UHFFFAOYSA-N

Angaben zum Gen

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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Verwandte Kategorien

Allgemeine Beschreibung

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Terazosin Hydrochloride belongs to the class of a1-adrenergic blockers, widely used for the treatment of benign prostatic hyperplasia (BPH) affecting the urogenital tract in men.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

It may be used as drug standard stock solution for determination of terazosin hydrochloride dihydrate using potentiometric and fluorimetric techniques.
Terazosin Hydrochloride may be used as a drug standard stock solution for the determination of terazosin hydrochloride dihydrate using potentiometric and fluorimetric techniques.
Terazosin Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance thin layer chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA7395 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Y0000622

Terazosin impurity A, European Pharmacopoeia (EP) Reference Standard

1643463

Terazosin-verwandte Verbindung A, United States Pharmacopeia (USP) Reference Standard

1643474

Terazosin-verwandte Verbindung B, United States Pharmacopeia (USP) Reference Standard

1643485

Terazosin-verwandte Verbindung C, United States Pharmacopeia (USP) Reference Standard

Y0000621

Terazosin -hydrochlorid Dihydrat, European Pharmacopoeia (EP) Reference Standard

Y0000665

Terazosin Unreinheit E, European Pharmacopoeia (EP) Reference Standard

Y0000624

Terazosin Unreinheit N, European Pharmacopoeia (EP) Reference Standard

1643452

Terazosin -hydrochlorid, United States Pharmacopeia (USP) Reference Standard

Y0000666

Terazosin for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard

PHR3137

Terazosin Related Compound A, certified reference material, pharmaceutical secondary standard

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H319

Gefahreneinstufungen

Eye Irrit. 2

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAD4384
LRAC1985
LRAA7395

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Die Dokumentenbibliothek aufrufen

Validated HPTLC method for the simultaneous determination of alfuzosin, terazosin, prazosin, doxazosin and finasteride in pharmaceutical formulations
Belal.ST, et al.
Analytical Chemistry Research, 1, 23-31 (2014)
Terazosin potentiometric sensor for quantitative analysis of terazosin hydrochloride in pharmaceutical formulation based on computational study.
Hosseini, Morteza, Ensieh Nasli-Esfahani, and Parviz Norouzi.
International Journal of Electrochemical Science, 5, 200-214 (2010)
Potentiometric and fluorimetric methods for the determination of terazosin HCl in drug substance and dosage forms.
Ismail, Nahla S., and Taghreed A. Mohamed.
International Journal of Electrochemical Science, 9, 7394-7394 (2014)

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