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PHR1710

Supelco

Cetirizin-Hydrochlorid-verwandte Verbindung A

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Cetirizin-ethylester -dihydrochlorid, (RS)-2-[2-[4-[(4-Chlorphenyl)-phenylmethyl]-piperazin-1-yl]-ethoxy]-essigsäure-ethylester -dihydrochlorid

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About This Item

Empirische Formel (Hill-System):
C23H29ClN2O3 · 2HCl
CAS-Nummer:
Molekulargewicht:
489.86
EG-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to USP 1102930

API-Familie

cetirizine

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 40 mg

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

-10 to -25°C

InChI

1S/C23H29ClN2O3/c1-2-29-22(27)18-28-17-16-25-12-14-26(15-13-25)23(19-6-4-3-5-7-19)20-8-10-21(24)11-9-20/h3-11,23H,2,12-18H2,1H3

InChIKey

ASHQTVRYHSZGQY-UHFFFAOYSA-N

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Allgemeine Beschreibung

Cetirizine hydrochloride Related Compound A is an impurity of cetirizine hydrochloride. Cetirizine hydrochloride is a second-generation antihistamine compound. It is a major metabolite of hydroxyzine that exhibits high specific affinity for histamine H1 receptor. It is used for the management of allergies, hay fever, angioedema, and urticaria.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Cetirizine hydrochloride has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA7298 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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Piktogramme

Exclamation markEnvironment

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Choose from one of the most recent versions:

Analysenzertifikate (COA)

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Cetirizin -dihydrochlorid European Pharmacopoeia (EP) Reference Standard

C0980650

Cetirizin -dihydrochlorid

Cetirizin für die Peakidentifizierung European Pharmacopoeia (EP) Reference Standard

Y0001197

Cetirizin für die Peakidentifizierung

Cetirizin -dihydrochlorid ≥98% (HPLC)

Sigma-Aldrich

C3618

Cetirizin -dihydrochlorid

Norphenylephrin-Hydrochlorid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1536

Norphenylephrin-Hydrochlorid

Phenylephrin-Hydrochlorid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1017

Phenylephrin-Hydrochlorid

Simultaneous quantitation and validation of paracetamol, phenylpropanolamine hydrochloride and cetirizine hydrochloride by RP-HPLC in bulk drug and formulation
Suryan AL, et al.
International Journal of Pharmaceutical Sciences and Drug Research, 3(4), 303-308 (2011)
Determination and quantification of cetirizine HCl in dosage formulations by RP-HPLC
Wankhede SB, et al.
International Journal of Pharmaceutical Sciences and Drug Research, 4(3), 222-226 (2012)
Development and Validation of RP-HPLC Method for Simultaneous Estimation of Cetirizine Hydrochloride and Phenylpropanolamine Hydrochloride in Tablet Dosage Form.
Dhongle PS, et al.
Research Journal of Pharmacy and Technology, 4(9), 1471-1474 (2011)
RP-HPLC and spectrophotometric estimation of ambroxol hydrochloride and cetirizine hydrochloride in combined dosage form.
Bhatia NM, et al.
Indian Journal of Pharmaceutical Sciences, 70(5), 603-603 (2008)
Determination and quantification of cetirizine HCl in dosage formulations by RP-HPLC.
ARAYNE MS, et al.
Science, 1(4), 1-4 (2005)

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