Alle Fotos(1)

Dokumente

PHR1398

Betamethason

Name: Betamethason
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Betamethason, 9α-Fluor-11β,17α,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion, 9α-Fluor-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion, 9α-Fluor-16β-methylprednisolon

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):

C₂₂H₂₉FO₅

CAS-Nummer:

378-44-9

Molekulargewicht:

392.46

EG-Nummer:

206-825-4

MDL-Nummer:

MFCD00062969

UNSPSC-Code:

41116107

PubChem Substanz-ID:

329823372

NACRES:

NA.24

Empfohlene Produkte

Slide 1 of 10

1 of 10

Supelco

PHR1399

Betamethasondipropionat

Sigma-Aldrich

B7005

Betamethason

USP

1066009

Betamethason

B1000000

Betamethason

Supelco

PHR1376

Loratadin

Supelco

PHR1014

Hydrocortison

Supelco

PHR1526

Dexamethason

Supelco

PHR1619

Beclomethasondipropionat

B1040000

Betamethasondipropionat

USP

1067704

Betamethasondipropionat

Biologische Quelle

synthetic

Qualitätsniveau

300

Qualität

certified reference material
pharmaceutical secondary standard

Agentur

BP
EP
USP
traceable to BP 575
traceable to Ph. Eur. B1000000
traceable to USP 1066009

Dampfdruck

<0.0000001 kPa ( 25 °C)

API-Familie

betamethasone

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 1 g

Lagerbedingungen

protect from light (20 mm aluminium crimp seal for unused portion)

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Farbe

white to light yellow

mp (Schmelzpunkt)

235-237 °C (lit.)

Löslichkeit

acetone: sparingly soluble
chloroform: very slightly soluble
ethanol: sparingly soluble
ether: very slightly soluble
methanol: sparingly soluble
water: insoluble

Dichte

0.305 g/cm³ at 25 °C (77°F)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Versandbedingung

ambient

Lagertemp.

2-30°C

SMILES String

[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChIKey

UREBDLICKHMUKA-DVTGEIKXSA-N

Angaben zum Gen

human ... NR3C1(2908)

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Betamethasone belongs to the corticosteriod family of active pharmaceutical ingredients (APIs). It exhibits anti-inflammatory activity and hence is used in the manufacture of various finished pharmaceutical products and is also employed as a starting material to manufacture other APIs that are related to this steroid family.

Anwendung

Betamethasone may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by using micellar liquid chromatography technique and reversed-phase high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA2174 in the slot below. This is an example certificate only and may not be the lot that you receive.

Signalwort

Danger

H-Sätze

H360FD,H373

P-Sätze

P202 - P260 - P280 - P308 + P313 - P405 - P501

Gefahreneinstufungen

Repr. 1B - STOT RE 2

Zielorgane

Liver,Kidney,Endocrine system

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Kunden haben sich ebenfalls angesehen

Slide 1 of 8

1 of 8

USP

1173508

Desoximetason

Supelco

PHR1043

Prednisolon

Supelco

PHR1619

Beclomethasondipropionat

Sigma-Aldrich

B7652

Betamethason 21-Phosphat Dinatriumsalz

Supelco

PHR1376

Loratadin

Supelco

PHR1014

Hydrocortison

B1140000

Bisacodyl

Supelco

PHR1810

Tadalafil

Simultaneous determination of dexamethasone and betamethasone in pharmaceuticals by reversed-phase HPLC

Pena-Garcia-Brioles D, et al.

Chromatographia, 39(9), 539-542 (1994)

Development and validation of a stability-indicating RP-HPLC method for assay of betamethasone and estimation of its related compounds

Fu Q, et al.

Journal of Pharmaceutical and Biomedical Analysis, 51(3), 617-625 (2010)

Development and validation of a stability-indicating RP-HPLC method to separate low levels of dexamethasone and other related compounds from betamethasone

Xiong Y, et al.

Journal of Pharmaceutical and Biomedical Analysis, 49(3), 646-654 (2009)

Method development for betamethasone and dexamethasone by micellar liquid chromatography using cetyl trimethyl ammonium bromide and validation in tablets: Application to cocktails

Pena-Garcia-Brioles D, et al.

Journal of Pharmaceutical and Biomedical Analysis, 36(1), 65-71 (2004)

Steroids in aminoglycoside-containing ear drops: do they reduce cochlear toxicity?

Brian W Blakley et al.

The Laryngoscope, 124(5), 1209-1213 (2013-10-22)

To determine whether betamethasone (BM) reduces the cochlear toxicity of otic gentamicin (GM) if given together. Controlled animal study. Thirty-four mice were assigned at random to receive intratympanic injections of either 0.1 % BM (11 mice), 0.3% GM (13 mice)

Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.

Dokumente

Betamethason

Pharmaceutical Secondary Standard; Certified Reference Material

About This Item

Empfohlene Produkte

Eigenschaften

Biologische Quelle

Qualitätsniveau

Qualität

Agentur

Dampfdruck

API-Familie

Analysenzertifikat (CofA)

Verpackung

Lagerbedingungen

Methode(n)

Farbe

mp (Schmelzpunkt)

Löslichkeit

Dichte

Anwendung(en)

Format

Versandbedingung

Lagertemp.

SMILES String

InChI

InChIKey

Angaben zum Gen

Verwandte Kategorien

Beschreibung

Allgemeine Beschreibung

Anwendung

Hinweis zur Analyse

Sonstige Hinweise

Fußnote

Verwandte Produkte

Ähnliches Produkt

Sicherheitshinweise

Piktogramme

Signalwort

H-Sätze

P-Sätze

Gefahreneinstufungen

Zielorgane

WGK

Flammpunkt (°F)

Flammpunkt (°C)

Dokumentation

Analysenzertifikate (COA)

Besitzen Sie dieses Produkt bereits?

Kunden haben sich ebenfalls angesehen

Peer-Reviewed-Artikel

Technischer Dienst