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Merck

PHR1351

Supelco

myo-Inositol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

i-Inosit, meso-Inosit

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About This Item

Empirische Formel (Hill-System):
C6H12O6
CAS-Nummer:
Molekulargewicht:
180.16
Beilstein:
1907329
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to Ph. Eur. Y0000485
traceable to USP 1340960

Dampfdichte

6.2 (vs air)

API-Familie

inositol

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

222-227 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

O[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4+,5-,6-

InChIKey

CDAISMWEOUEBRE-GPIVLXJGSA-N

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Allgemeine Beschreibung

Inositol is a structural isomer of glucose and a sugar alcohol. It is known to be a remedy for mild depression and neurasthenia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Bestandteil von Membranphospholipiden, Glycosyl­phosphatidyl­inositol-Ankern, welche Glykoproteine mit Zellmembranen verbinden und dem Second Messenger Inositoltriphosphat.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3650 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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D-chiro-Inosit ≥98.0% (HPLC)

Sigma-Aldrich

74137

D-chiro-Inosit

L-(−)-chiro-Inositol 95%

Sigma-Aldrich

468053

L-(−)-chiro-Inositol

Cholinchlorid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1251

Cholinchlorid

Betain -hydrochlorid certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

90910

Betain -hydrochlorid

Parteck® SI 450 (Sorbit) EMPROVE® ESSENTIAL, NF, FCC, JSFA

SAFC

1.03557

Parteck® SI 450 (Sorbit)

Folsäure ≥97%

Sigma-Aldrich

F7876

Folsäure

Natural medications for psychiatric disorders : considering the alternatives (2008)
Dietmar Weichert et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(29), 10744-10748 (2014-07-10)
Structural studies on G protein-coupled receptors (GPCRs) provide important insights into the architecture and function of these important drug targets. However, the crystallization of GPCRs in active states is particularly challenging, requiring the formation of stable and conformationally homogeneous ligand-receptor
Sookhee Bang et al.
Molecular endocrinology (Baltimore, Md.), 28(7), 1186-1193 (2014-06-01)
Metformin is a biguanide drug that is widely prescribed for type 2 diabetes. Metformin suppresses hepatic gluconeogenesis and increases fatty acid oxidation. Although studies have suggested that metformin acts, at least in part, via activation of the liver kinase B1
Dora Lippai et al.
Alcoholism, clinical and experimental research, 38(8), 2217-2224 (2014-08-27)
Chronic alcohol impairs gut barrier function and induces inflammatory cytokines. The effects of acute alcohol binge on the gut are partially understood. Micro-RNA-155 (miR-155), a modulator of cytokine and T-cell immune response in the gut, stabilizes tumor necrosis factor-α (TNFα)
Nkateko M I Mayevu et al.
Molecular and cellular endocrinology, 402, 95-106 (2015-01-15)
Transmembrane helix seven residues of G protein-coupled receptors (GPCRs) couple agonist binding to a conserved receptor activation mechanism. Amino-terminal residues of the GnRH peptide determine agonist activity. We investigated GnRH interactions with the His(7.36(305)) residue of the GnRH receptor, using

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