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PHR1277

Supelco

Nitrilotriessigsäure

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Nitrilotriessigsäure, N,N-Bis-(carboxymethyl)-glycin, NTA, Tris-(carboxymethyl)-amin

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About This Item

Lineare Formel:
N(CH2COOH)3
CAS-Nummer:
139-13-9
Molekulargewicht:
191.14
Beilstein:
1710776
EG-Nummer:
205-355-7
MDL-Nummer:
MFCD00004287
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823273
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to USP 1463950

API-Familie

edta

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

245 °C (dec.) (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

OC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

InChIKey

MGFYIUFZLHCRTH-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Nitrilotriacetic acid (NTA) is a polyaminopolycarboxylic acid, widely used as a synthetic chelating agent. It forms stable and water-soluble chelates with different metals. It is used as a detergent builder to soften water and for masking metal ions in various industrial processes.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
ausgezeichnetes chelatbildendes Reagens

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3702 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Piktogramme

Health hazardExclamation mark
GHS08,GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

WGK

WGK 2

Flammpunkt (°F)

closed cup

Flammpunkt (°C)

closed cup

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAC8964
LRAC3702
LRAA9074
LRAA0013

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Determination of nitrilotriacetic acid and ethylenediaminetetraacetic acid in environmental samples as their methyl ester derivatives by gas chromatography-mass spectrometry
Nishikawa Y and Okumura T
Journal of Chromatography A, 690(1), 109-118 (1995)
The determination of part-per-billion levels of citric and nitrilotriacetic acids in tap water and sewage effluents
Aue WA, et al.
Journal of Chromatography A, 72(2), 259-267 (1972)
Quantitative gas chromatographic determination of nitrilotriacetic acid in the presence of other carboxylic acids
Larson RA, et al.
Journal of Chromatography A, 111(1), 43-49 (1975)
Determination of the solubility products of nitrilotriacetic acid, ethylenediaminetetraacetic acid and diethylenetriaminepentaacetic acid.
Karhu J, et al.
Analytica Chimica Acta, 380(1), 105-111 (1999)
Asgar Abbas Kazrani et al.
Nucleic acids research, 42(9), 5929-5936 (2014-03-19)
PvuRts1I is a prototype for a larger family of restriction endonucleases that cleave DNA containing 5-hydroxymethylcytosine (5hmC) or 5-glucosylhydroxymethylcytosine (5ghmC), but not 5-methylcytosine (5mC) or cytosine. Here, we report a crystal structure of the enzyme at 2.35 Å resolution. Although
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