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PHR1227

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Fluorouracil

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

5-Fluorouracil, 2,4-Dihydroxy-5-Fluoropyrimidin, 5-FU, 5-Fluor-2,4(1H,3H)-pyrimidindion

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About This Item

Empirische Formel (Hill-System):
C4H3FN2O2
CAS-Nummer:
51-21-8
Molekulargewicht:
130.08
Beilstein:
127172
EG-Nummer:
200-085-6
MDL-Nummer:
MFCD00006018
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823233
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to BP 995
traceable to Ph. Eur. F0250000
traceable to USP 12790000

API-Familie

fluorouracil

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

282-286 °C (dec.) (lit.)

Anwendung(en)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

FC1=CNC(=O)NC1=O

InChI

1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)

InChIKey

GHASVSINZRGABV-UHFFFAOYSA-N

Angaben zum Gen

human ... TYMS(7298)

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Verwandte Kategorien

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Fluorouracil, an analog of the pyrimidines, belongs to the class of antimetabolite drugs. It is generally utilized for the remediation of tumors such as breast adenocarcinoma, gastrointestinal tract, ovary, head and neck.

Anwendung

Fluorouracil may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by different analytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3468 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Fluoruracil-verwandte Verbindung E, United States Pharmacopeia (USP) Reference Standard

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Fluorouracil-verwandte Verbindung A, United States Pharmacopeia (USP) Reference Standard

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Fluoruracil-verwandte Verbindung B, United States Pharmacopeia (USP) Reference Standard

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Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

H-Sätze

H301 - H351

Gefahreneinstufungen

Acute Tox. 3 Oral - Carc. 2

Lagerklassenschlüssel

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAC3468
LRAD0121
LRAA9039
P500227

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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