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PHR1218

Supelco

trans-Anethol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

4-Propenylanisol, trans-1-Methoxy-4-propenyl-benzol

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About This Item

Lineare Formel:
CH3CH=CHC6H4OCH3
CAS-Nummer:
Molekulargewicht:
148.20
Beilstein:
774229
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to USP 1035005

API-Familie

anethole

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.561 (lit.)

bp

234-237 °C (lit.)

mp (Schmelzpunkt)

20-21 °C (lit.)

Dichte

0.988 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

COc1ccc(\C=C\C)cc1

InChI

1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+

InChIKey

RUVINXPYWBROJD-ONEGZZNKSA-N

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Allgemeine Beschreibung

trans-Anethole is an aromatic monoterpenoid compound and derivative of phenylpropene. It is predominantly used as a fragrance in cosmetics and as a flavoring agent in food and pharmaceutical industries.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Anwendung

trans-Anethole may be used as an analytical reference standard for the determination of the analyte in raw material, food products and pharmaceutical formulations by high performance liquid chromatography and gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Natürlich vorkommendes Phenylpropen-Derivat das in geringerer Konzentration Estrogen und in höherer Konzentration zytotoxisch auf Krebszellenlinien wirkt. Die Cytotoxizität beruht auf dem Metabolismus des trans-Anethol zu 4-Hydroxy-1-propenylbenzol.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This compound is commonly found in plants of the genus: pimpinella

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC3326 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Warning

H-Sätze

Gefahreneinstufungen

Aquatic Chronic 2 - Skin Sens. 1

WGK

WGK 2


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Analysenzertifikate (COA)

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Arachidonsäure from non-animal source, ≥98.5% (GC)

Sigma-Aldrich

A3611

Arachidonsäure

p-Anisaldehyd 98%

Sigma-Aldrich

A88107

p-Anisaldehyd

Anethole
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 40(1)(3-4), 5576-5576 (2018)
Fast quantitative determination of volatile constituents in fennel by headspace-gas chromatography
Krizman M, et al.
Analytica Chimica Acta, 557(1-2), 267-271 (2006)
LC determination of anethole in aniseed drinks
Jurado JM, et al.
Chromatographia, 64(3-4), 223-226 (2006)
Identification by HPLC- DAD and HPLC- MS analyses and quantification of constituents of fennel teas and decoctions
Bilia AR, et al.
Journal of Agricultural and Food Chemistry, 48(10), 4734-4738 (2000)
Determination of trans-anethole in Salvia sclarea essential oil by liquid chromatography and GC-MS
Fiori J, et al
Journal of Separation Science, 25(10-11), 703-709 (2002)

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