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PHR1197

Supelco

Iminostilben

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

5H-Dibenz[b,f]azepin, Iminostilben

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About This Item

Empirische Formel (Hill-System):
C14H11N
CAS-Nummer:
256-96-2
Molekulargewicht:
193.24
Beilstein:
1343358
EG-Nummer:
205-970-0
MDL-Nummer:
MFCD00005071
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823205
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to USP 1093023

API-Familie

carbamazepine, oxcarbazepine 

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

196-199 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

N1c2ccccc2C=Cc3ccccc13

InChI

1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H

InChIKey

LCGTWRLJTMHIQZ-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards..

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA9013 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

H-Sätze

H302 - H411

P-Sätze

P273

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Chronic 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAD1317
LRAC4932
LRAA9013
P500197

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

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Sigma-Aldrich

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Koleta Hemine et al.
Carbohydrate polymers, 250, 116957-116957 (2020-10-15)
It is widely believed that the hydrophobic effect governs the binding of guest molecules to cyclodextrins (CDs). However, it is also known that high hydrophobicity of guest molecules does not always translate to the formation of stable inclusion complexes with
S M Furst et al.
Biochemical pharmacology, 45(6), 1267-1275 (1993-03-24)
Carbamazepine is an anticonvulsant which is associated with a significant incidence of hypersensitivity reactions including agranulocytosis. We have postulated that many drug hypersensitivity reactions, especially agranulocytosis and lupus, are due to reactive metabolites generated by the myeloperoxidase (MPO) (EC 1.11.1.7)
A Varenne et al.
Journal of immunological methods, 186(2), 195-204 (1995-10-26)
As part of our ongoing work to extend the range of applications of the non-isotopic carbonyl metalloimmunoassay (CMIA), previously developed in our laboratory, we describe here the first CMIA study of carbamazepine. The CMIA method uses a metal carbonyl complex
Ying Wu et al.
The Journal of allergy and clinical immunology, 118(1), 233-241 (2006-07-04)
T-cell-mediated hypersensitivity is a rare but serious manifestation of drug therapy. To explore the mechanisms of drug presentation to T cells and the possibility that generation of metabolite-specific T cells may provoke cross-sensitization between drugs. A lymphocyte transformation test was
S M Furst et al.
Drug metabolism and disposition: the biological fate of chemicals, 23(5), 590-594 (1995-05-01)
Carbamazepine therapy is associated with several types of idiosyncratic drug reactions, including hematological disorders. In previous studies, we found that carbamazepine was metabolized by the myeloperoxidase/H2O2 system of activated neutrophils, and covalent binding of the drug to neutrophils was observed.
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