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PHR1156

Supelco

Tributyl-2-Acetylcitrat

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Acetyltributylcitrat

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About This Item

Lineare Formel:
CH3CO2C[CO2(CH2)3CH3][CH2CO2(CH2)3CH3]2
CAS-Nummer:
77-90-7
Molekulargewicht:
402.48
Beilstein:
2303316
EG-Nummer:
201-067-0
MDL-Nummer:
MFCD00043554
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329823174
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

300

Agentur

traceable to Ph. Eur. Y0001055
traceable to USP 1009901

Dampfdruck

0.26 psi ( 20 °C)
0.8 psi ( 55 °C)

Beschreibung

API family: acetyltributyl citrate

API-Familie

acetyltributyl citrate

Analysenzertifikat (CofA)

current certificate can be downloaded

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Brechungsindex

n20/D 1.443 (lit.)

Dichte

1.05 g/mL at 25 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

CCCCOC(=O)CC(CC(=O)OCCCC)(OC(C)=O)C(=O)OCCCC

InChI

1S/C20H34O8/c1-5-8-11-25-17(22)14-20(28-16(4)21,19(24)27-13-10-7-3)15-18(23)26-12-9-6-2/h5-15H2,1-4H3

InChIKey

QZCLKYGREBVARF-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Tributyl 2-acetylcitrate is a hydrophobic biodegradable plasticizer, that is usually synthesized by esterification of citric acid. Pharmaceutically, it is used as an excipient, which is generally applied as a thin film over the tablets or capsules.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Tributyl 2-acetylcitrate may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by gas chromatography.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAA8991 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

422.6 °F - closed cup

Flammpunkt (°C)

217 °C - closed cup

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
LRAC3222
LRAA8991
P500156

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Tributylcitrat ≥97.0%

Sigma-Aldrich

27497

Tributylcitrat

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Study of the migration behavior of acetyl tributyl citrate from PVDC/PVC film into fish fillets as affected by intermediate doses of electron beam radiation
Zygoura PD, et al.
European Food Research and Technology, 232(6), 1017-1025 (2011)
Acetyltributyl Citrate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 35(6)(4), 3833-3834 (2017)
Acetyltributyl Citrate
Pharmacopeia, US
United States Pharmacopeia/National Formulary, 35(6)(4), 5555-5555 (2018)
Pharmacokinetic Properties of Acetyl Tributyl Citrate, a Pharmaceutical Excipient
Kim H, et al.
Pharmaceutics, 10(4), 177-177 (2018)
Migration of di-(2-ethylhexyl) adipate (DEHA) and acetyl tributyl citrate (ATBC) plasticizers from PVC film into the food stimulant of isooctane: Weichmacherwanderung von Di-(2-ethylhexyl) Adipate (DEHA) und Acetyl Tributyl Zitrate (ATBC) von PVC-Folien in das Genussmittel Isooctan
Lajqi MV, et al.
Materials Science and Engineering Technology, 46(1), 16-23 (2015)
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