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I1887

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Indapamid

analytical standard, for drug analysis

Synonym(e):

N-(4-Chlor-3-sulfamoylbenzamido)-2-methylindolin

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About This Item

Empirische Formel (Hill-System):
C16H16ClN3O3S
CAS-Nummer:
26807-65-8
Molekulargewicht:
365.83
EG-Nummer:
248-012-7
MDL-Nummer:
MFCD00079375
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329815359
NACRES:
NA.24

Qualität

analytical standard, for drug analysis

Qualitätsniveau

100

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(N)(=O)=O

InChI

1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)

InChIKey

NDDAHWYSQHTHNT-UHFFFAOYSA-N

Angaben zum Gen

human ... SLC12A3(6559)

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Allgemeine Beschreibung

Indapamide is a deuretic drug, belonging to the class of benzothiadiazines. It is commonly used for the treatment of hypertension. The drug acts by causing a drop in systolic, diastolic and mean blood pressure.

Anwendung

Indapamide may be used as an internal standard for the quantification of the analyte in pharmaceutical formulations and biological samples using different analytical techniques
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Anwendung

Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

Health hazard
GHS08

Signalwort

Warning

H-Sätze

H361d,H362

Gefahreneinstufungen

Lact. - Repr. 2

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number
BCCD6339
BCCB3713
BCBZ6736
BCBW4383
BCBN5690V

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2′-Chloracetophenon 97%

Sigma-Aldrich

183709

2′-Chloracetophenon

(±)-Metoprolol ≥98% (titration), powder

Sigma-Aldrich

M5391

(±)-Metoprolol

Susan van Dieren et al.
Diabetes research and clinical practice, 98(1), 83-90 (2012-06-09)
To asses differences in treatment effects of a fixed combination of perindopril-indapamide on major clinical outcomes in patients with type 2 diabetes across subgroups of cardiovascular risk. 11,140 participants with type 2 diabetes, from the ADVANCE trial, were randomized to
Alina Porfire et al.
Journal of pharmaceutical and biomedical analysis, 70, 301-309 (2012-08-14)
This paper describes the development and application of NIR-chemometric methods for active content assay and pharmaceutical characterization (granulometric analysis and flowability assessment) of indapamide powder blends for tabletting. Indapamide powder blends were prepared and their NIR spectra were recorded in
N Beckett et al.
BMJ (Clinical research ed.), 344, d7541-d7541 (2012-01-06)
To assess if very elderly people with hypertension obtain early benefit from antihypertensive treatment. One year open label active treatment extension of randomised controlled trial (Hypertension in the Very Elderly Trial (HYVET)). Hospital and general practice based centres mainly in
Simultaneous estimation of amlodipine besylate and indapamide in a pharmaceutical formulation by a high performance liquid chromatographic (RP-HPLC) method
Patel.BD, et al.
Scientia Pharmaceutica, 80(3), 581-590 (2012)
A selective HPLC method for the determination of indapamide in human whole blood: Application to a bioequivalence study in Chinese volunteers
Hang J-T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(1), 202-205 (2006)
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