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I0460000

Isoleucin

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

L-Isoleucin, (2S,3S)-2-Amino-3-methyl-valeriansäure

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About This Item

Lineare Formel:
C2H5CH(CH3)CH(NH2)CO2H
CAS-Nummer:
73-32-5
Molekulargewicht:
131.17
Beilstein:
1721792
MDL-Nummer:
MFCD00064222
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329815310
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

leucine

Hersteller/Markenname

EDQM

mp (Schmelzpunkt)

288 °C (dec.) (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

CC[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

InChIKey

AGPKZVBTJJNPAG-WHFBIAKZSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Isoleucine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Beschreibung
Preisangaben

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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L-Isoleucin from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

I7403

L-Isoleucin

DL-allo-Isoleucin ≥99.0%

Sigma-Aldrich

05706

DL-allo-Isoleucin

Millipore

Millipore

1.05362

L-Isoleucin

L-Leucin from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

L8912

L-Leucin

Prolin European Pharmacopoeia (EP) Reference Standard

P3350000

Prolin

L-Leucin reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

L-Leucin

O Søvik
Journal of inherited metabolic disease, 16(1), 46-54 (1993-01-01)
A review is presented of 22 published cases of verified or probable mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency, a disorder of isoleucine and ketone body metabolism. The clinical expression, characterized by ketoacidosis, vomiting and lethargy, is highly variable. Typical age of onset
Stanley H Korman
Molecular genetics and metabolism, 89(4), 289-299 (2006-09-05)
Three inborn errors have been identified in the pathway of isoleucine degradation. Deficiency of beta-ketothiolase (beta-KT, also known as T2, mitochondrial acetoacetyl-CoA thiolase and acetyl-CoA acetyltransferase 1) is a well-described disorder which presents with acute episodic ketoacidosis. In contrast, short/branched-chain
O A Mamer
Journal of chromatography. B, Biomedical sciences and applications, 758(1), 49-55 (2001-08-03)
The initial catabolic steps of isoleucine by mammals has been misunderstood and misapprehended in the scientific literature for many years. The suggestion that the interconversion of isoleucine and alloisoleucine occurs through the keto-enol racemization of their respective transaminated alpha-keto acids
Vijay Joshi et al.
Amino acids, 39(4), 933-947 (2010-02-27)
Pathways regulating threonine, methionine and isoleucine metabolism are very efficiently interconnected in plants. As both threonine and methionine serve as substrates for isoleucine synthesis, their synthesis and catabolism under different developmental and environmental conditions also influence isoleucine availability. Together, methionine
Jirí Svoboda et al.
Phytochemistry, 71(13), 1445-1449 (2010-06-24)
Our understanding of plant defensive mechanisms against herbivore and pathogen attack has significantly increased over the past decade. The complex cascade of defensive events is initiated and controlled by a network of interacting plant hormones. Especially, the conjugate of jasmonate
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Protokolle

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

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