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Merck

G1522

Sigma-Aldrich

Gentamicin

solution, suitable for hybridoma, BioReagent

Synonym(e):

Garamycin, Gentiomycin C

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352207
eCl@ss:
42020823
PubChem Substanz-ID:
NACRES:
NA.76

product name

Gentamicin -Lösung, Hybri-Max, 50 mg/mL gentamicin, 0.1 μm filtered, BioReagent, suitable for hybridoma

Qualität

Hybri-Max
Prepared in tissue culture grade water.

Qualitätsniveau

Sterilität

0.1 μm filtered

Produktlinie

BioReagent

Form

liquid

Konzentration

50 mg/mL gentamicin

Methode(n)

cell culture | hybridoma: suitable

Verunreinigungen

endotoxin, tested

Farbe

colorless to light yellow

Dichte

1.000 g/cm3

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria
mycoplasma

Wirkungsweise

protein synthesis | interferes

Lagertemp.

2-8°C

SMILES String

OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O

InChI

1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1

InChIKey

RDEIXVOBVLKYNT-HDZPSJEVSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Chemical structure: aminoglycoside

Anwendung

Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.

Biochem./physiol. Wirkung

Wirkungsweise: Gentamicin hemmt die Proteinsynthese, indem es sich an die 30S-Untereinheit des Ribosoms bindet.

Antimikrobielles Spektrum: Unter anderem gramnegative und grampositive Bakterien, einschließlich Stämmen, die gegen Tetracyclin, Chloramphenicol, Kanamycin und Colistin resistent sind, insbesondere die Stämme Pseudomonas, Proteus, Staphylococcus und Streptococcus.

Komponenten

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.

Vorsicht

The product is stable at 37° for 5 days and is stored at 2-8°C.

Rechtliche Hinweise

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Ersetzt durch

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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Gentamicinsulfat

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