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Merck

F9005

Supelco

Flufenaminsäure

analytical standard, for drug analysis

Synonym(e):

N-(α,α,α-Trifluor-m-tolyl)-anthranilsäure, N-[3-(Trifluormethyl)-phenyl]-anthranilsäure

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About This Item

Lineare Formel:
2-(CF3C6H4NH)C6H4CO2H
CAS-Nummer:
Molekulargewicht:
281.23
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard, for drug analysis

Qualitätsniveau

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

132-135 °C (lit.)

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F

InChI

1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)

InChIKey

LPEPZBJOKDYZAD-UHFFFAOYSA-N

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Allgemeine Beschreibung

Flufenamic acid, a non-steroidal anti-inflammatory drug, is an effective analgesic agent.

Anwendung

Flufenamic acid has been used as a standard in studying the two well defined, polymorphs of flufenamic acid like form I and form III, using solid-state density functional theory and terahertz spectroscopy.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Skull and crossbones

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Analysenzertifikate (COA)

Lot/Batch Number

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Pharmaceutics, 11(3) (2019-03-22)
Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-DHPs. This study was designed to evaluate
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Cellular and molecular life sciences : CMLS, 77(3), 531-542 (2019-06-27)
Human bitter taste receptors (TAS2Rs) are a subfamily of 25 G protein-coupled receptors that mediate bitter taste perception. TAS2R14 is the most broadly tuned bitter taste receptor, recognizing a range of chemically diverse agonists with micromolar-range potency. The receptor is
Conformational origins of polymorphism in two forms of flufenamic acid
Delaney P S, et al.
Journal of Molecular Structure, 1078, 83-89 (2014)
Jon Andoni Sánchez et al.
Immunobiology, 222(2), 241-250 (2016-10-11)
Previous works with autumnalamide reported that Store Operated Calcium (SOC) channels were blocked through mitochondrial modulation. In the present paper we studied the effect of autumnalamide on ionomycin Ca2+ fluxes. Thus, autumnalamide did not modify ionomycin-sensitive intracellular pools while the
Julia C Schwarz et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 81(3), 557-562 (2012-05-09)
Microemulsions are thermodynamically stable, colloidal drug delivery systems. This study presents the first substantiated comparison of natural, skin-compatible and biodegradable surfactants in terms of their suitability to form isotropic microemulsions and their skin interaction. Pseudoternery phase diagrams were constructed for

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