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Merck

E0753

Supelco

4-Ethoxymethylen-2-phenyl-2-oxazolin-5-on

analytical standard, for drug analysis

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About This Item

Empirische Formel (Hill-System):
C12H11NO3
CAS-Nummer:
Molekulargewicht:
217.22
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard, for drug analysis

Qualitätsniveau

Assay

≥90% (HPLC)

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

94-96 °C (dec.) (lit.)

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Lagertemp.

2-8°C

SMILES String

CCO\C=C1/N=C(OC1=O)c2ccccc2

InChI

1S/C12H11NO3/c1-2-15-8-10-12(14)16-11(13-10)9-6-4-3-5-7-9/h3-8H,2H2,1H3/b10-8-

InChIKey

SJHPCNCNNSSLPL-NTMALXAHSA-N

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Anwendung

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Oxazolon sensitierendes Agens

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

P-Sätze

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Analysenzertifikate (COA)

Lot/Batch Number

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Sigma-Aldrich

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Supelco

Supelco

47118

Olivenöl

Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers
Haarder S, et al.
The Open Immunology Journal, 6, 154-154 (2016)
Ann Laigaard et al.
Scientific reports, 10(1), 21204-21204 (2020-12-05)
Atopic dermatitis is a chronic eczema commonly observed among children in Western countries. The gut microbiota is a significant factor in the pathogenesis, and ways to promote intestinal colonizers with anti-inflammatory capabilities are therefore favorable. The present study addressed the
Kenjyo Miyauchi et al.
Nature chemical biology, 9(2), 105-111 (2012-12-18)
N(6)-threonylcarbamoyladenosine (t(6)A) is a universally conserved, essential modified nucleoside found in transfer RNAs (tRNAs) responsible for ANN codons in all three domains of life. t(6)A has a crucial role in maintaining decoding accuracy during protein synthesis. The presence of t(6)A
Mijung Yeom et al.
Journal of dermatological science, 67(2), 101-110 (2012-06-26)
Irritant contact dermatitis (ICD) is an inflammatory skin disease triggered by exposure to a chemical that is toxic or irritating to the skin. A major characteristic of chronic ICD is an inflammatory dry-skin condition with associated itching. Although glucosylceramide (GlcCer)
Boyi Liu et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(9), 3549-3563 (2013-06-01)
Allergic contact dermatitis is a common skin disease associated with inflammation and persistent pruritus. Transient receptor potential (TRP) ion channels in skin-innervating sensory neurons mediate acute inflammatory and pruritic responses following exogenous stimulation and may contribute to allergic responses. Genetic

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