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D6924

Sigma-Aldrich

Dextransulfat Natriumsalz aus Leuconostoc spp.

average mol wt 9,000-20,000

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About This Item

CAS-Nummer:
9011-18-1
MDL-Nummer:
MFCD00081551
UNSPSC-Code:
12352201
NACRES:
NA.21

Biologische Quelle

bacterial (Leuconostoc mesenteroides)

Qualitätsniveau

200

Form

powder

Optische Aktivität

[α]/D 90 to 105 °, c = 6% (w/v)

Mol-Gew.

average mol wt 9,000-20,000

Zusammensetzung

Sulfur Content, 16.0-19.0%

Farbe

white to off-white

Nützlicher pH-Bereich

5.5 - 8.0

Löslichkeit

H2O: 100 mg/mL

Lagertemp.

room temp

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Verwandte Kategorien

Allgemeine Beschreibung

Dextran sulfate sodium is a natural polymer of α-1,6-D-glucopyranose. It is a hydrophilic, biodegradable, and biocompatible polyanionic polymer. This highly branched polysaccharide has 1,6 and 1,4 glycosidic linkages, consisting of 2.3 sulfate groups per glucosyl unit.

Anwendung

Dextran sulfate sodium salt from Leuconostoc spp. has been used:
  • to evaluate the participation of sulfated glycans on the interaction of recombinant human proacrosin/acrosin with zona pellucida (ZP) glycoproteins
  • to inject into the vitreous cavity of embryonic day five chick embryos to assess the eye size and to study its impact on cell proliferation in the retina
  • to test the structural specificity of binding of TNF-stimulated gene 6 (TSG-6) to immobilized hyaluronan (HA)

Biochem./physiol. Wirkung

Dextran sulfate may exhibit anti-coagulant and antiviral properties. It may also help to lower cholesterol levels. It is extensively used as a plasma volume expander and fibrinolytic in the medical field. Dextran sulfate can also be used as a cross-linker for chitosan (CH).

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Kundensupport

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Sigma-Aldrich

Sigma-Aldrich

31395

Dextransulfat Natriumsalz aus Leuconostoc spp.

Sigma-Aldrich

Sigma-Aldrich

75027

Dextransulfat Natriumsalz

Millipore

Millipore

265152-M

Dextransulfat, Natriumsalz, molekularbiologische Qualität

Sigma-Aldrich

Sigma-Aldrich

78331

FITC-Dextran-Sulfat Natriumsalz

SAFC

SAFC

RES6104H-A7

Hypoxanthin, Mononatriumsalz

Azoxymethan 13.4 M, ≥98%

Sigma-Aldrich

A5486

Azoxymethan

Willi Halfter
Investigative ophthalmology & visual science, 49(8), 3289-3298 (2008-03-26)
The vitreous body (VB) is a transparent, extracellular matrix structure that fills the vitreous cavity of the eye. Major constituents of the VB are hyaluronic acid (HA) and glycosaminoglycans (GAGs), both of which are highly charged, linear carbohydrate polymers. The
Yi-Nan Zhang et al.
ACS nano, 14(8), 9478-9490 (2020-06-02)
Nanovaccines need to be transported to lymph node follicles to induce humoral immunity and generate neutralizing antibodies. Here, we discovered that subcapsular sinus macrophages play a barrier role to prevent nanovaccines from accessing lymph node follicles. This is illustrated by
Jorge E Toblli et al.
Drug design, development and therapy, 9, 2585-2597 (2015-05-26)
Iron deficiency is common in inflammatory bowel disease, yet oral iron therapy may worsen the disease symptoms and increase systemic and local oxidative stress. The aim of this study was to compare the effects of oral ferrous sulfate and iron
Aaron H Rose et al.
Inflammatory bowel diseases, 21(9), 2005-2015 (2015-06-16)
An important role has emerged for calpain enzymes in regulating inflammation with one isoform, calpain-2, particularly important for macrophage activation. The goal of this study was to determine the therapeutic potential of a synthetic calpain-2 inhibitor, zLLY-CH2F, for colitis and

Artikel

Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Protokolle

Dextransulfat

Dextransulfate sind in Form ihrer Natriumsalze erhältlich, in der sie in Wasser löslich und stabil sind. Dextransulfat enthält ca. 17 % Schwefel, dies entspricht ungefähr 2,3 Sulfatgruppen pro Glucosylrest.

Dextran Sulfate

Dextran sulfates are supplied as the sodium salt forms, making them soluble and stable in water. Dextran sulfate contains approximately 17% sulfur which is equivalent to approximately 2.3 sulfate groups per glucosyl residue.

Verwandter Inhalt

Dextran and Related Polysaccharides

Learn about C6H10O6 or dextran formation, classes and naming from MilliporeSigma. Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, which have a linear backbone of α-linked d-glucopyranosyl repeating units.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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