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A92775

Sigma-Aldrich

Arsenazo III

calcium-sensitive dye, Powder

Synonym(e):

Arsenazo III Beckman®, Bis-(2-arsono-benzolazo)-2,7-chromotropsäure

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About This Item

Lineare Formel:
(HO)2C10H2(SO3H)2(N=NC6H4AsO3H2)2
CAS-Nummer:
1668-00-4
Molekulargewicht:
776.37
Beilstein:
5717957
EG-Nummer:
216-788-6
MDL-Nummer:
MFCD00036695
UNSPSC-Code:
12171500
PubChem Substanz-ID:
24891431
NACRES:
NA.47

product name

Arsenazo III, calcium-sensitive dye

Qualitätsniveau

200

Form

powder

Methode(n)

titration: suitable

Verunreinigungen

<0.1% Ca

Farbe

brown to very dark brown, and Black

mp (Schmelzpunkt)

>320 °C (lit.)

Löslichkeit

ammonium hydroxide: 1 mg/mL

λmax

530 nm

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

Oc1c(\N=N\c2ccccc2[As](O)(O)=O)c(cc3cc(c(\N=N\c4ccccc4[As](O)(O)=O)c(O)c13)S(O)(=O)=O)S(O)(=O)=O

InChI

1S/C22H18As2N4O14S2/c29-21-18-11(9-16(43(37,38)39)19(21)27-25-14-7-3-1-5-12(14)23(31,32)33)10-17(44(40,41)42)20(22(18)30)28-26-15-8-4-2-6-13(15)24(34,35)36/h1-10,29-30H,(H2,31,32,33)(H2,34,35,36)(H,37,38,39)(H,40,41,42)/b27-25+,28-26+

InChIKey

UQHVTNUJRKELCE-NBHCHVEOSA-N

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Anwendung

Arsenazo III has been used as a color forming reagent to determine uranium concentration.

Biochem./physiol. Wirkung

Arsenazo III is a metallochromic dye. Arsenazo III is used in the determination of calcium in biological samples. It is used to evaluate calcium transport in permeabilized cells. It is also used for the detection of rare earth metals (polyvalent metal ions). Arsenazo III is used for the spectrophotometric determination of uranium and thorium.

Piktogramme

Skull and crossbonesEnvironment
GHS06,GHS09

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Daniel T Holmes et al.
American journal of clinical pathology, 151(3), 328-336 (2018-11-27)
The Hoffmann method is a procedure for reference interval estimation using routine clinical results. Many authors incorrectly prepare Hoffmann plots on a linear rather than normal probability scale. We explore the consequences. This was investigated algebraically, by random number simulations
Analytica Chimica Acta, 71, 375-375 (1974)
J W Janssen et al.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 29(3), 197-201 (1991-03-01)
The widely used calcium dye reagent, o-cresolphthalein complexone, was replaced by the less well known metallochromic indicator Arsenazo III in a selective multitest analyser. Calibration stability increased from 12 hours to more than 48 hours. With the Arsenazo III reagent
L J Dong et al.
Fresenius' journal of analytical chemistry, 370(8), 1009-1014 (2001-10-05)
The determination of proteins with arsenazo-DBN and Al3+ by Rayleigh light-scattering (RLS) is described. The weak RLS of arsenazo-DBN and BSA can be enhanced greatly by addition of Al3+ in the pH range 5.3-7.0; this resulted in two enhanced RLS
Phosphatidate and oxidized fatty acids are calcium ionophores. Studies employing arsenazo III in liposomes.
Serhan C, et al.
The Journal of Biological Chemistry, 256, 2736-2741 (1981)
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