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A3139

Sigma-Aldrich

Albumin aus Mausserum

lyophilized powder, ≥96% (agarose gel electrophoresis)

Synonym(e):

Mausalbumin

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About This Item

CAS-Nummer:
9048-46-8
EG-Nummer:
232-936-2
MDL-Nummer:
MFCD00804573
UNSPSC-Code:
12352202
NACRES:
NA.27

Biologische Quelle

mouse

Qualitätsniveau

200

Assay

≥96% (agarose gel electrophoresis)

Form

lyophilized powder

Methode(n)

ELISA: suitable
electrophoresis: suitable

UniProt-Hinterlegungsnummer

P07724

Lagertemp.

2-8°C

Angaben zum Gen

mouse ... ALB(11657)

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Allgemeine Beschreibung

Mouse albumin gene is mapped to mouse chromosome 5. It codes for an albumin, which is the most prominent protein in the blood plasma. Albumin is produced by the mature liver. Mouse albumin gene promoter region includes minimum six binding sites (A to F) for specific DNA-binding proteins.

Anwendung

Albumin from mouse serum has been used in labelling by probe 2 for the characterization of matrix metalloprotease-12 by one-dimensional electrophoresis. It has also been used for the preparation of calibrator and controls in enzyme-linked immunosorbent assay (ELISA).

Biochem./physiol. Wirkung

Albumin facilitates the formation of cytoplasmic lipid droplets in pancreatic stellate cells and adipocyte differentiation of 3T3-L1 cells. In addition, it effectively regulates biological activity of adipogenic transcription factors, peroxisome proliferator-activated receptor (PPAR - γ ) and (CCAAT/enhancer binding protein (C/EBP).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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Analysenzertifikate (COA)

Lot/Batch Number

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Plasma

Albumin expression is required for adipocyte differentiation of 3T3-L1 cells
Yoo W, et al.
Biochemical and biophysical research communications, 397(2), 170-175 (2010)
Detection of endogenous matrix metalloprotease-12 active form with a novel broad spectrum activity-based probe
Nury C, et al.
The Journal of biological chemistry, 288(8), 5636-5644 (2013)
Softened food reduces weight loss in the streptozotocin-induced male mouse model of diabetic nephropathy
Norgaard SA, et al.
Laboratory Animals, 52(4), 373-383 (2018)
Albumin-binding domain from Streptococcus zooepidemicus protein Zag as a novel strategy to improve the half-life of therapeutic proteins
Cantante C, et al.
Journal of Biotechnology, 253(6), 23-33 (2017)
Distant enhancers stimulate the albumin promoter through complex proximal binding sites
Vorachek WR, et al.
Test, 275(37), 29031-29041 (2000)
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