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A0230000

Adenin

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

6-Amino-purin, Vitamin B4

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About This Item

Empirische Formel (Hill-System):
C5H5N5
CAS-Nummer:
73-24-5
Molekulargewicht:
135.13
Beilstein:
5777
MDL-Nummer:
MFCD00041790
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329770588
NACRES:
NA.24

Biologische Quelle

synthetic

Qualität

pharmaceutical primary standard

Agentur

EP

API-Familie

adenine

Form

solid

Hersteller/Markenname

EDQM

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp (Schmelzpunkt)

>360 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChIKey

GFFGJBXGBJISGV-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Adenine belongs to the group of purine alkaloids widely distributed in plant products and beverages. It can be used as an internal microbial marker for the determination of microbial protein synthesis.

Anwendung

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Kann Verkaufsbeschränkungen unterliegen.

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Preisangaben

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301

Gefahreneinstufungen

Acute Tox. 3 Oral

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Choose from one of the most recent versions:

Analysenzertifikate (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

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Guanin 98%

Sigma-Aldrich

G11950

Guanin

Thymin ≥99%

Sigma-Aldrich

T0376

Thymin

Adenosin ≥99%

Sigma-Aldrich

A9251

Adenosin

Simultaneous determination of adenine and guanine in ruminant bacterial pellets by ion-pair HPLC
Moral dGP, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 826(1-2), 257-260 (2005)
Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection
Meyer A, et al.
Fresenius Journal of Analytical Chemistry, 356(3-4), 284-287 (1996)
Didier Wion et al.
Nature reviews. Microbiology, 4(3), 183-192 (2006-02-21)
N(6)-methyl-adenine is found in the genomes of bacteria, archaea, protists and fungi. Most bacterial DNA adenine methyltransferases are part of restriction-modification systems. Certain groups of Proteobacteria also harbour solitary DNA adenine methyltransferases that provide signals for DNA-protein interactions. In gamma-proteobacteria
Caroline Pabst et al.
Nature methods, 11(4), 436-442 (2014-02-25)
Leukemic stem cells (LSCs) are considered a major cause of relapse in acute myeloid leukemia (AML). Defining pathways that control LSC self-renewal is crucial for a better understanding of underlying mechanisms and for the development of targeted therapies. However, currently
Ravindra K Gupta et al.
The Journal of infectious diseases, 207 Suppl 2, S101-S106 (2013-05-25)
Recent data from studies on treatment as prevention (TasP) and preexposure prophylaxis (PrEP) show that antiretroviral drugs can be used in prevention, as well as in treatment. The movement from first-generation antiretroviral therapy (ART) coformulations based on thymidine analogues to
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