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Merck

62248

Supelco

2-[4-(1-Hydroxy-2-methylpropyl)-phenyl]-propansäure

pharmaceutical impurity standard

Synonym(e):

1-Hydroxyibuprofen, Ibuprofen impurity L (PhEur), 2-[4-(1-Hydroxy-2-methyl-propyl)-phenyl]-propionsäure

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About This Item

Empirische Formel (Hill-System):
C13H18O3
CAS-Nummer:
Molekulargewicht:
222.28
Beilstein:
22307543
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualitätsniveau

Assay

≥98.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Verunreinigungen

≤0.5% water

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

CC(C)C(O)c1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9,12,14H,1-3H3,(H,15,16)

InChIKey

RMOQYHYFRKTDRI-UHFFFAOYSA-N

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Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Ibuprofen ≥98% (GC)

Sigma-Aldrich

I4883

Ibuprofen

Chloé S Baron et al.
Cell, 179(2), 527-542 (2019-10-05)
Much of current molecular and cell biology research relies on the ability to purify cell types by fluorescence-activated cell sorting (FACS). FACS typically relies on the ability to label cell types of interest with antibodies or fluorescent transgenic constructs. However
Chi-Yeh Chung et al.
Cell reports, 29(2), 495-510 (2019-10-10)
Technological improvements enable single-cell epigenetic analyses of organ development. We reasoned that high-resolution single-cell chromatin accessibility mapping would provide needed insight into the epigenetic reprogramming and transcriptional regulators involved in normal mammary gland development. Here, we provide a single-cell resource
Dobeen Hwang et al.
Cell chemical biology, 26(9), 1229-1239 (2019-06-25)
Homogeneous antibody-drug conjugates (ADCs) that use a highly reactive buried lysine (Lys) residue embedded in a dual variable domain (DVD)-IgG1 format can be assembled with high precision and efficiency under mild conditions. Here we show that replacing the Lys with
Tanner O Monroe et al.
Developmental cell, 48(6), 765-779 (2019-02-19)
Specialized adult somatic cells, such as cardiomyocytes (CMs), are highly differentiated with poor renewal capacity, an integral reason underlying organ failure in disease and aging. Among the least renewable cells in the human body, CMs renew approximately 1% annually. Consistent
Kamila Burdova et al.
The EMBO journal, 38(20), e101443-e101443 (2019-08-20)
Cyclins are central engines of cell cycle progression in conjunction with cyclin-dependent kinases (CDKs). Among the different cyclins controlling cell cycle progression, cyclin F does not partner with a CDK, but instead forms via its F-box domain an SCF (Skp1-Cul1-F-box)-type

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