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Merck

50194

Supelco

Sulisobenzon

analytical standard

Synonym(e):

5-Benzoyl-4-hydroxy-2-methoxybenzolsulfonsäure, 2-Hydroxy-4-methoxy-benzophenon-5-sulfonsäure, HMBS, Sulisobenzon

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About This Item

Empirische Formel (Hill-System):
C14H12O6S
CAS-Nummer:
Molekulargewicht:
308.31
Beilstein:
2889165
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥97.5% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

cleaning products
cosmetics
environmental
food and beverages
personal care

Format

neat

SMILES String

COc1cc(O)c(cc1S(O)(=O)=O)C(=O)c2ccccc2

InChI

1S/C14H12O6S/c1-20-12-8-11(15)10(7-13(12)21(17,18)19)14(16)9-5-3-2-4-6-9/h2-8,15H,1H3,(H,17,18,19)

InChIKey

CXVGEDCSTKKODG-UHFFFAOYSA-N

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Allgemeine Beschreibung

Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulisobenzone may be used as an analytical reagent for the determination of the analyte in sunscreen formulations by high-performance liquid chromatography with UV spectrophotometric detection.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 1

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available


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Analysenzertifikate (COA)

Lot/Batch Number

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Determination of UV-filters in sunscreens by HPLC.
Chisvert A, et al.
Fresenius Journal of Analytical Chemistry, 369(7-8), 638-641 (2001)
S M Edwards et al.
Photodermatology, photoimmunology & photomedicine, 10(3), 111-117 (1994-06-01)
The ability to accurately predict the phototoxic potential of personal and skin care products remains a key element in assessing the safety of premarketed products. To find a reliable in vitro alternative test for photoirritancy, the European Commission and the
M Jarratt et al.
Journal of the American Academy of Dermatology, 9(3), 354-360 (1983-09-01)
A PABA ester-oxybenzone preparation is superior to PABA or sulisobenzone alone in protecting the skin from methoxsalen-induced ultraviolet A (UVA) phototoxicity after water substantivity challenge. Such a mixture would be useful as a UVA screen for uninvolved or actinically damaged
C Augustin et al.
Photodermatology, photoimmunology & photomedicine, 13(1-2), 27-36 (1997-02-01)
Phototoxicity inducing in vivo photoirritation, a reversible inflammatory reaction of the skin after chemical contact and UVA radiation exposure, is increasingly observed as a side effect associated with the use of both cosmetics and systemic drugs. In order to systematically
Zacarías León et al.
Analytica chimica acta, 664(2), 178-184 (2010-04-07)
2-Hydroxy-4-methoxybenzophenone and 2-hydroxy-4-methoxybenzophenone-5-sulphonic acid, commonly known as benzophenone-3 (BZ3) and benzophenone-4 (BZ4), respectively, are substances widely used as UV filters in cosmetic products in order to absorb UV radiation and protect human skin from direct exposure to the deleterious wavelengths

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