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Merck

439223

Sigma-Aldrich

Dichlormethan

suitable for HPLC, ≥99.9%, contains 40-150 ppm amylene as stabilizer

Synonym(e):

Methylenchlorid

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About This Item

Empirische Formel (Hill-System):
CH2Cl2
CAS-Nummer:
Molekulargewicht:
84.93
Beilstein:
1730800
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12190000
PubChem Substanz-ID:
NACRES:
NA.21

Dampfdichte

2.9 (vs air)

Qualitätsniveau

Dampfdruck

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

Assay

≥99.9%

Form

liquid

Selbstzündungstemp.

1223 °F

Enthält

40-150 ppm amylene as stabilizer

Expl.-Gr.

22 %

Methode(n)

HPLC: suitable

Verunreinigungen

Free halogens, passes test
≤0.0003 meq/g Titr. acid
≤0.02% water

Abdampfrückstand

<0.0003%

Farbe

APHA: ≤10
clear

Brechungsindex

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp (Schmelzpunkt)

−95 °C (lit.)

Dichte

1.325 g/mL at 25 °C (lit.)

λ

H2O reference

UV-Absorption

λ: 235 nm Amax: 1.00
λ: 240 nm Amax: 0.20
λ: 250 nm Amax: 0.05
λ: 260 nm Amax: 0.02
λ: 340-400 nm Amax: 0.01

Eignung

passes test for HPLC

SMILES String

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChIKey

YMWUJEATGCHHMB-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Dichloromethane (DCM) is a chlorinated organic solvent with a wide range of industrial applications. It has C2v symmetry, low boiling point, high density and is immiscible in water. Degradation of DCM by various methods has been reported. Ultrasonic absorption studies of liquid DCM shows strong relaxation effect. A study reports the dielectric characteristics of DCM over a wide frequency range. DCM is susceptible to degradation with time, which can be suppressed by adding amylene as a stabilizer.

Anwendung

entspricht den ACS-Spezifikationen
Dichloromethane (Methylene chloride) may be used in the following processes:
  • To compose ultrasonic baths for cleaning and protection of aluminum coating over atactic-PMMA (poly(methyl methacrylate)) for dielectric studies.
  • Preparation of AMBF3 (ammoniomethyltrifluoroborate)-conjugated biomolecules.
  • Sample preparation for GC-MS (Gas Chromatography-Mass Spectrometry) analysis.
  • Preparation of ammonium acetate solvent mixture in combination with isopropanol, acetonitrile and water for mass spectral analysis of neutral lipids.
  • Quantification of glutathione (GSH) and glutathione disulfide (GSSG) in biological samples by HPLC and spectrophotometry.
  • As an extractant for 2,2-dithioethyl-4-(2′-pyridyl)-4-butyro-γ-lactone.

Angaben zur Herstellung

filtriert durch einen 0.2 μm Filter

Piktogramme

Health hazardExclamation mark

Signalwort

Warning

Gefahreneinstufungen

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Central nervous system

WGK

WGK 2

Flammpunkt (°F)

does not flash

Flammpunkt (°C)

does not flash

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Daniela Giustarini et al.
Nature protocols, 8(9), 1660-1669 (2013-08-10)
This protocol describes a procedure for determining glutathione (GSH) and glutathione disulfide (GSSG) concentrations in blood and other tissues. Artifactual oxidation to GSSG of 5-15% of the GSH found in a sample can occur during deproteination of biological samples with
Rodney C Baker et al.
Methods in enzymology, 538, 89-105 (2014-02-18)
Mass spectrometry technology has enabled significant advances in detailing the alterations of the lipidome in response to pathological conditions or experimental manipulations. Lipids comprise a wide range of compounds with functions that include structural, intracellular signaling, trafficking, and storage. Characterization
Jane A Mullaney et al.
Journal of agricultural and food chemistry, 61(12), 3039-3046 (2013-03-07)
Glucosinolates from the genus Brassica can be converted into bioactive compounds known to induce phase II enzymes, which may decrease the risk of cancers. Conversion via hydrolysis is usually by the brassica enzyme myrosinase, which can be inactivated by cooking
Vitamin B12-mediated hydrodechlorination of dichloromethane by bimetallic Cu/Al particles.
Huang CC, et al.
Chemical Engineering Journal, 273, 413-420 (2015)
Dichloromethane Detection Based on Near-Infrared Absorptive Sensing.
Han JH and Yoon SM
IEEE Journal of Selected Topics in Quantum Electronics, 18(5), 1547-1552 (2012)

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