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Supelco

Microcystin-LR -Lösung

10 μg/mL in methanol, analytical standard

Synonym(e):

Cyanoginosin, Fast-death factor

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About This Item

Empirische Formel (Hill-System):
C49H74N10O12
CAS-Nummer:
101043-37-2
Molekulargewicht:
995.17
EG-Nummer:
200-659-6
MDL-Nummer:
MFCD01774058
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329754699
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Haltbarkeit

limited shelf life, expiry date on the label

Konzentration

10 μg/mL in methanol

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Format

single component solution

Lagertemp.

−20°C

SMILES String

CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(C)\C=C\[C@@H]2NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]2C)C(O)=O)C(O)=O

InChI

1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28-31,34-38,40H,8,14,17,20-23,25H2,1-7,9-10H3,(H,53,64)(H,54,65)(H,55,62)(H,56,61)(H,57,63)(H,58,66)(H,67,68)(H,69,70)(H4,50,51,52)/b19-18+,27-24+/t28-,29-,30-,31+,34-,35-,36+,37-,38-,40+/m0/s1

InChIKey

ZYZCGGRZINLQBL-GWRQVWKTSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Microcystin-LR belongs to the group of cyclic heptapeptide metabolites called microcystins, produced by cyanobacterium (blue-green algae) Microcystis aeruginosa, and others.

Anwendung

The analytical standard can also be used as follows:

  • Development of a paper immunosensor based on nanobiochar particles (nBC) and anti-microcystin-LR monoclonal antibodies (mAbs) for the identification of microcystin-LR in environmental water samples
  • Determination of microcystin-LR in tap water samples using a lateral flow immunochromatographic assay (LFICA) procedure based on molecularly imprinted polymers and enzyme-assisted color change approach
  • Fluorescence-based detection of microcystin-LR in tap water and serum samples by an aptasensor, constructed using single-walled carbon nanotubes (SWNTs) and dapoxyl fluorescent dye
  • Analysis of surface water samples for the detection of microcystin-LR using ultra high-performance liquid chromatography-mass spectrometry (UHPLC-MS) and high-performance liquid chromatography-variable wavelength-Ultraviolet Detector (HPLC-VW-UVD) methods
  • Determination of microcystin-LR in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).

Sonstige Hinweise

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes

WGK

WGK 2

Flammpunkt (°F)

51.8 °F

Flammpunkt (°C)

11 °C

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves

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Analysenzertifikate (COA)

Lot/Batch Number
BCCK2672
BCCJ1204
BCCG5365
BCCF9964
BCCD8845

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[D-Asp3, (E)-Dhb7]-Microcystin-RR -Lösung

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Here we present a new analytical method where immunoconcentration of the analyte is coupled to quantitative matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) analysis allowing in minutes the identification and highly sensitive quantitation of microcystins (MCs)
Michele Pelosi et al.
Journal of lipid research, 58(12), 2348-2364 (2017-10-08)
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Keke Zhang et al.
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This work reveals the deleterious effect of microcystin-LR (MC-LR) on the conformation of DNA and develops an electrochemical biosensor for detection of MC-LR. The biosensor is prepared by physically immobilizing calf thymus DNA (ctDNA) on gold electrode. In the presence
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Blood transferrin receptor-positive (TfR+) exosomes are a kind of optimized drug delivery vector compared with other kinds of exosomes due to their easy access and high bio-safety. Their application facilitates the translation from bench to bedside of exosome-based delivery vehicles.
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