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MAB570

Sigma-Aldrich

Anti-Heparin Antibody, clone A7.10

clone A7.10, Chemicon®, from mouse

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

A7.10, monoclonal

Speziesreaktivität

mouse

Darf nicht reagieren mit

pig

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
radioimmunoassay: suitable

Isotyp

IgG2b

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Hdgf(15191)

Spezifität

Reacts with mouse heparin. Cross reacts with dextran sulfate by EIA. Also shows some cross reactivity to DNA and heparan sulfate.

Anwendung

Research Category
Zellstruktur
Research Sub Category
ECM-Proteine
Detect Heparin using this Anti-Heparin Antibody, clone A7.10 validated for use in ELISA, RIA.
EIA/RIA (kd by liquid phase RIA for heparin is approximately

1.0 x 10-11 M.) Suggested concentration 1-10 μg/mL.

Inhibits the formation of heparin accelerated thrombin-antithrombin complex formation in vitro.

Optimal working dilutions must be determined by end user.

Physikalische Form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB + 0.25M NaCl, pH 7.6 with 0.1% Sodium azide.

Lagerung und Haltbarkeit

Maintain at 2-8°C.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Autoimmune MRL mice express high-affinity IgG2b monoclonal autoantibodies to heparin.
Fillit, H, et al.
Clinical Immunology and Immunopathology, 81, 62-67 (1996)
J Qiu et al.
Virology, 269(1), 137-147 (2000-03-22)
Recently heparan sulfate was proposed as the host cell receptor for the dependovirus, adeno-associated virus type 2 (AAV2). We show that although heparan sulfate on the cell surface may contribute to the binding of AAV2 to permissive cells, the amount
E Ortega-Barria et al.
The Journal of biological chemistry, 274(3), 1267-1276 (1999-01-09)
Toxoplasma gondii is one of the most widespread parasites of humans and animals. The parasite has a remarkable ability to invade a broad range of cells within its mammalian hosts by mechanisms that are poorly understood at the molecular level.

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