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AB1936

Sigma-Aldrich

Anti-Integrin α2 Antibody

serum, Chemicon®

Synonym(e):

CD49b

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

chicken, rat, hamster, mouse, human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

NM_002203.3

UniProt-Hinterlegungsnummer

P17301

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ITGA2(3673)

Spezifität

Human alpha2 integrin subunit. Specificity determined by immunoprecipitation from a detergent extract of 35S methionine labeled endothelial cells. The epitope recognized is on the cytoplasmic domain of the protein and is thus intracellular. Shows no cross-reactivity to alpha1, alpha3, alpha4, alpha5, alpha6, or alphaV subunits.

Immunogen

Synthetic peptide derived from the COOH terminal sequence (cytoplasmic domain) of the human alpha2 integrin subunit {KYEKMTKNPDEODETTELSS}

Anwendung

Research Category
Zellstruktur
Research Sub Category
Integrine
Anti-Integrin α2 Antibody detects level of Integrin α2 & has been published & validated for use in ELISA, IF, IH, IP, RIA & WB.
Immunofluorescence: 1:500 (suggested for use on acetone-fixed tissue only)

ELISA/RIA: 1:1000

Western blot: 1:1000 The antibody has been used to report alpha2 expression in HUVECs during tubule-like structure formation in collagen (Deroanne, 1996). Recognizes ~160kDa alpha 2 subunit

Immunoprecipitation: 5 μL precipitates alpha2/beta1 from 5 x 106 cells.

Immunohistochemistry: 1:500

Optimal working dilutions must be determined by end user.

Zielbeschreibung

160kDa

Physikalische Form

Unpurified
Neat rabbit antiSerum. Liquid with 0.05% sodium azide

Lagerung und Haltbarkeit

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hinweis zur Analyse

Control
Skin (basement membrane), High grade ovarian tumors

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Altered cytoskeleton organization in platelets from patients with MYH9-related disease.
I Canobbio, P Noris, A Pecci, A Balduini, C L Balduini, M Torti
Journal of Thrombosis and Haemostasis null
Saccharomyces boulardii Improves Intestinal Cell Restitution through Activation of the ?2?1 Integrin Collagen Receptor.
Canonici, Alexandra, et al.
Testing, 6, e18427-e18427 (2011)
C F Deroanne et al.
Cardiovascular research, 49(3), 647-658 (2001-02-13)
This investigation aimed at determining the importance of the rigidity of the adhesive support and the participation of the cytoskeleton in tubulogenesis of endothelial cells in vitro. The morphotype, biosynthetic phenotype and cytoskeleton organization of human umbilical vein endothelial cells
Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas.
Bai R, Siu IM, Tyler BM, Staedtke V, Gallia GL, Riggins GJ
Neuro-Oncology null
Core3 glycan as tumor suppressor.
Lee SH, Fukuda M
Test null
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