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07-1406

Sigma-Aldrich

Anti-GLUT-5 Antibody, a.a. 490-502

serum, from rabbit

Synonym(e):

Fructose transporter, Glucose transporter type 5, small intestine, glucose transporter-like protein 5, solute carrier family 2 (facilitated glucose transporter),

member 5, solute carrier family 2 (facilitated glucose/fructose

transporte

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

rat, guinea pig, mouse

Methode(n)

western blot: suitable

UniProt-Hinterlegungsnummer

P22732

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Slc2A5(56485)

Allgemeine Beschreibung

A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels.

Spezifität

Recognizes GLUT-5.

Immunogen

Epitope: C-terminus
Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse.

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Insulin-/stoffwechselassoziierte Signalübertragung
Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB.

Qualität

Evaluated by Western Blot in Mouse kidney lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.

Zielbeschreibung

Approx. 54 kDa

Verlinkung

Replaces: AB1348

Physikalische Form

Unpurified rabbit serum
Liquid containing 0.05% sodium azide.

Lagerung und Haltbarkeit

Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles.

Hinweis zur Analyse

Control
Mouse kidney lysate.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Irene Zwarts et al.
Scientific reports, 9(1), 9299-9299 (2019-06-28)
Fructose has become a major constituent of our modern diet and is implicated as an underlying cause in the development of metabolic diseases. The fructose transporter GLUT5 (SLC2A5) is required for intestinal fructose absorption. GLUT5 expression is induced in the
Ana Andres-Hernando et al.
Cell metabolism, 32(1), 117-127 (2020-06-06)
Intake of fructose-containing sugars is strongly associated with metabolic syndrome. Compared with other sugars, dietary fructose is uniquely metabolized by fructokinase. However, the tissue-specific role of fructokinase in sugar-induced metabolic syndrome, and the specific roles of glucose and fructose in

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