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Merck

M-160

Supelco

(±)-4-Methylephedrine-D3 hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C11H14D3NO · HCl
Molekulargewicht:
218.74
EG-Nummer:
UNSPSC-Code:
41116107

Qualität

certified reference material

Qualitätsniveau

Form

liquid

Leistungsmerkmale

(Snap-N-Spike®)

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

Konzentration

100 μg/mL in methanol (as free base)

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

forensics and toxicology

Format

single component solution

Lagertemp.

−20°C

SMILES String

CC(NC([2H])([2H])[2H])C(O)C1=CC=C(C)C=C1.Cl

InChI

1S/C11H17NO.ClH/c1-8-4-6-10(7-5-8)11(13)9(2)12-3;/h4-7,9,11-13H,1-3H3;1H/i3D3;

InChIKey

DDFKODAFZRBBOK-FJCVKDQNSA-N

Allgemeine Beschreibung

A bath salt cathinone analog and primary urinary metabolite of mephedrone. Mephedrone, also known as 4-methylmethcathinone, is a synthetic cathinone and stimulant widely found in numerous bath salt blends across the US, Europe, and Asia. This certified Snap-N-Spike® solution is suitable as an internal standard for quantitation of (±)-4-Methylephedrine by LC/MS or GC/MS for applications in urine drug testing, clinical toxicology, or forensic testing.

Anwendung


  • (±)-4-Methylephedrine-D₃ hydrochloride as an analytical standard: This compound is extensively used as a stable isotope-labeled standard in mass spectrometry, enhancing the accuracy and precision of analytical methods for detecting and quantifying ephedrine and its derivatives in complex biological matrices. Its role is crucial in doping control, forensic analysis, and therapeutic drug monitoring (Deshpande et al., 2024).

  • Pharmaceutical research applications: In pharmaceutical research, (±)-4-Methylephedrine-D₃ hydrochloride is employed to study the pharmacokinetics and metabolism of ephedrine-based drugs. Its deuterated form provides an internal standard that is vital for achieving reliable quantification in bioanalytical studies, particularly in the development of new therapeutic agents.

  • Enhancing mass spectrometry techniques: The use of (±)-4-Methylephedrine-D₃ hydrochloride in mass spectrometry significantly improves the method′s sensitivity and specificity. This is especially important in the field of toxicology and pharmacology, where precise measurements are essential for understanding drug behavior and ensuring patient safety.

  • Studying chiral drug interactions: As a chiral compound, (±)-4-Methylephedrine-D₃ hydrochloride aids in the research of stereoselective drug interactions, which are crucial for developing safer and more effective pharmaceutical formulations. This application helps in distinguishing the different enantiomers of chiral drugs and their distinct pharmacological effects.

  • Development of bioanalytical methods: This high-purity deuterated compound is used for developing and validating robust bioanalytical methods in biochemistry studies. It ensures that the analytical methods used in clinical and pharmacological research are both accurate and reproducible, facilitating the assessment of drug efficacy and safety in biological systems.

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Zielorgane

Eyes

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

49.5 °F

Flammpunkt (°C)

9.7 °C


Zulassungslistungen

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EU REACH Annex XVII (Restriction List)

CAS No.

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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