Direkt zum Inhalt
Merck

W224502

Sigma-Aldrich

Carvacrol

≥98%, FCC, FG

Synonym(e):

5-Isopropyl-2-methyl-phenol

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About This Item

Lineare Formel:
(CH3)2CHC6H3(CH3)OH
CAS-Nummer:
Molekulargewicht:
150.22
FEMA-Nummer:
2245
Beilstein:
1860514
EG-Nummer:
CoE-Nummer:
2055
MDL-Nummer:
UNSPSC-Code:
12164502
PubChem Substanz-ID:
Flavis-Nummer:
4.031
NACRES:
NA.21

Biologische Quelle

synthetic

Qualitätsniveau

Qualität

FG
Fragrance grade
Halal
Kosher

Agentur

follows IFRA guidelines
meets purity specifications of JECFA

Einhaltung gesetzlicher Vorschriften

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

Assay

≥98%

Brechungsindex

n20/D 1.522 (lit.)

bp

236-237 °C (lit.)

mp (Schmelzpunkt)

3-4 °C (lit.)

Dichte

0.976 g/mL at 20 °C (lit.)

Anwendung(en)

flavors and fragrances

Dokumentation

see Safety & Documentation for available documents

Nahrungsmittelallergen

no known allergens

Allergener Duftstoff

no known allergens

Organoleptisch

camphoraceous; woody; spicy

SMILES String

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

InChIKey

RECUKUPTGUEGMW-UHFFFAOYSA-N

Angaben zum Gen

human ... UGT1A4(54657)

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Verwandte Kategorien

Allgemeine Beschreibung

Carvacrol is a monoterpene compound that can be used as a flavoring agent in food and cosmetics. It is one of the major volatile components in oregano essential oil.

Anwendung


  • Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics.: This review explores the synthesis, characterization, and biological activities of carvacrol and thymol hybrids, highlighting their potential as anticancer and antibacterial agents. The study emphasizes the significance of these compounds in developing novel therapeutic strategies (Peter et al., 2024).

  • Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: This review investigates the role of essential oil constituents, including carvacrol, in modulating microglial activity. The findings suggest significant anti-inflammatory and neuroprotective effects, providing insights into their potential therapeutic applications in neuroinflammatory diseases (Stojanović et al., 2024).

  • Evidence of the Protective Role of Carvacrol in a Retinal Degeneration Animal Model.: This study demonstrates the protective effects of carvacrol in a retinal degeneration model. The results indicate that carvacrol can mitigate retinal damage and preserve retinal function, suggesting its potential as a therapeutic agent for retinal diseases (Inda et al., 2024).

  • Phytochemical Characterization and Biological Activities of Essential Oil from Satureja montana L., a Medicinal Plant Grown under the Influence of Fertilization and Planting Dates.: This study characterizes the essential oil of Satureja montana, rich in carvacrol, and evaluates its biological activities. The findings indicate significant antimicrobial and antioxidant properties, suggesting its potential in pharmaceutical and agricultural applications (Said-Al Ahl et al., 2024).

Haftungsausschluss

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Lagerklassenschlüssel

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flammpunkt (°F)

212.0 °F

Flammpunkt (°C)

> 100 °C

Persönliche Schutzausrüstung

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Supelco

Supelco

CRM40188

Thymol -Lösung

Thymol European Pharmacopoeia (EP) Reference Standard

T1350000

Thymol

Sigma-Aldrich

Sigma-Aldrich

W306509

Thimianöl

(R)-(−)-Carvon 98%

Sigma-Aldrich

124931

(R)-(−)-Carvon

Thymol analytical standard

Supelco

72477

Thymol

Eugenol natural, ≥98%, FG

Sigma-Aldrich

W246719

Eugenol

Carvacrol-methylether phyproof® Reference Substance

PHL83363

Carvacrol-methylether

Antimicrobial activity of carvacrol: current progress and future prospectives
Nostro A & Papalia T
Recent Patents on Anti-Cancer Drug Discovery, 7(1), 28-35 (2012)
The natural antimicrobial carvacrol inhibits Campylobacter jejuni motility and infection of epithelial cells
Van Alphen LB, et al
PLoS ONE, 7(9), e45343-e45343 (2012)
Yuhua Chang et al.
Journal of agricultural and food chemistry, 61(37), 8906-8913 (2013-09-04)
A simple cost-effective method (spontaneous emulsification) for fabricating physically stable antimicrobial nanoemulsions from essential oils is described. These nanoemulsions (10 wt % total oil phase) were formed by titration of a mixture of essential oil (carvacrol), carrier oil (medium chain
Bo Tang et al.
Oncogene, 38(20), 3946-3961 (2019-01-30)
Although VPAC1 and its ligand vasoactive intestinal peptide (VIP) are important in gastrointestinal physiology, their involvements in progression of gastrointestinal tumor have not been explored. Here, we found that higher expression of VIP/VPAC1 was observed in gastric cancer compared to
Wei-Zhe Liang et al.
Toxicology, 303, 152-161 (2012-11-14)
Carvacrol is one of the main substances of essential oil which triggers intracellular Ca(2+) mobilization and causes cytotoxicity in diverse cell models. However, the mechanism of carvacrol-induced Ca(2+) movement and cytotoxicity is not fully understood. This study examined the effect

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