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Merck

67520

Sigma-Aldrich

1-Methyl-L-histidin

≥98.0% (TLC), for peptide synthesis

Synonym(e):

3-(1-Methylimidazol-4-yl)-L-alanin, 3-Methyl-L-histidin (veraltet), Nτ-Methyl-L-histidin

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C7H11N3O2
CAS-Nummer:
Molekulargewicht:
169.18
Beilstein:
9727
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352209
PubChem Substanz-ID:
NACRES:
NA.22

product name

1-Methyl-L-histidin, ≥98.0% (TLC)

Qualitätsniveau

Assay

≥98.0% (TLC)

Form

powder

Optische Aktivität

[α]20/D −24±1°, c = 2% in H2O

Eignung der Reaktion

reaction type: solution phase peptide synthesis

Verunreinigungen

≤5% water

mp (Schmelzpunkt)

~240 °C (dec.) (lit.)

Anwendung(en)

peptide synthesis

SMILES String

Cn1cnc(C[C@H](N)C(O)=O)c1

InChI

1S/C7H11N3O2/c1-10-3-5(9-4-10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1

InChIKey

BRMWTNUJHUMWMS-LURJTMIESA-N

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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Sigma-Aldrich

C7505

L-Cystathionin

Histidin European Pharmacopoeia (EP) Reference Standard

H0750000

Histidin

P C Colombani et al.
International journal of sport nutrition, 9(2), 181-201 (1999-06-11)
A field study was performed to investigate the acute influence of a milk protein hydrolysate supplemented drink (CHO+PRO) on metabolism during and after a marathon run compared to the same drink without protein (CHO). Carbohydrate metabolites and hormones were not
3-Methylhistidine as a measure of skeletal muscle protein breakdown in human subjects: the case for its continued use.
F J Ballard et al.
Clinical science (London, England : 1979), 65(3), 209-215 (1983-09-01)
K Giesecke et al.
Metabolism: clinical and experimental, 38(12), 1196-1200 (1989-12-01)
Endogenous excretion of nitrogenous products was studied during early starvation in six healthy, nonobese subjects after six days on a well-defined diet, designed to achieve net protein balance and an adequate calorie supply. The diet contained 0.5 g myofibrillar-free protein
J Sjölin et al.
Metabolism: clinical and experimental, 38(1), 23-29 (1989-01-01)
The present investigation was undertaken in order to determine the release of 3-methylhistidine (3MH) from the splanchnic region and from the leg, and the contributions these make to the increase in urinary 3MH excretion in infection. Thirteen febrile patients with
P Betto et al.
Journal of chromatography, 584(2), 256-260 (1992-12-23)
A reversed-phase high-performance liquid chromatographic method is described for the determination of 3-methylhistidine content in human urine using pre-column derivatization with phenylisothiocyanate, isocratic elution with 15 mM sodium acetate-acetonitrile (92:8, v/v) and electrochemical detection. The limit of quantitation was 0.1

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