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Merck

535311

Sigma-Aldrich

Poly(N-isopropylacrylamid)

Mn ~40,000

Synonym(e):

NIPAM-Polymer, PNIPAM, Polyacrylamid, polyNIPAM

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About This Item

Lineare Formel:
CH3(C6H11NO)nCH3
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
PubChem Substanz-ID:
NACRES:
NA.23

Mol-Gew.

Mn 20,000-60,000
Mn ~40,000

Qualitätsniveau

mp (Schmelzpunkt)

96 °C

SMILES String

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

InChIKey

WDFKEEALECCKTJ-UHFFFAOYSA-N

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Anwendung

Wärmeempfindliches Polymer, das zur Bildung eines Hydrogels verwendet werden kann. Die wässrige Polymerlösung durchläuft einen Phasenübergang von einem löslichen zu einem unlöslichen Zustand, wenn die Temperatur auf etwa 32 °C angehoben wird.

Physikalische Form

Wärmeempfindliches Polymer, Hydrogel

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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N-Isopropylmethacrylamid 97%

Sigma-Aldrich

423548

N-Isopropylmethacrylamid

Manuel Pernia Leal et al.
ACS nano, 6(12), 10535-10545 (2012-11-03)
We report a procedure to grow thermo-responsive polymer shells at the surface of magnetic nanocarriers made of multiple iron oxide superparamagnetic nanoparticles embedded in poly(maleic anhydride-alt-1-ocatadecene) polymer nanobeads. Depending on the comonomers and on their relative composition, tunable phase transition
Albert J de Graaf et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 582-590 (2012-09-14)
In this paper it is shown that when a thermosensitive hydrogel based on poly(N-isopropylacrylamide)-poly(ethylene glycol)-poly(N-isopropylacrylamide) (pNIPAm-PEG-pNIPAm) was transferred into water, flower-like micelles were continuously released as long as the medium was regularly refreshed. On the other hand, if the medium
Guiying Li et al.
International journal of biological macromolecules, 50(4), 899-904 (2012-06-09)
Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introducing hydrophilic NVP. The
Jinseok Byun et al.
Chemical communications (Cambridge, England), 48(74), 9278-9280 (2012-08-09)
We report a novel approach for the fabrication of a photo-responsive surface with fast and reversibly switchable wettability between hydrophobicity and hydrophilicity induced by a photothermal effect.
Pengju Pan et al.
Langmuir : the ACS journal of surfaces and colloids, 28(40), 14347-14356 (2012-09-28)
Linear and miktoarm star-shaped diblock copolymers consisting of single-stranded DNA and poly(N-isopropylacrylamide) (PNIPAAm) with various compositions were synthesized via atom transfer radical polymerization and click chemistry. The temperature-responsive phase transition behavior, micellization, was systematically examined using UV-vis spectrometry, high-sensitivity differential

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