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436240

Sigma-Aldrich

Brij® 98

average Mn ~1,150

Synonym(e):

Polyoxyethylen (20)oleylether

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About This Item

Lineare Formel:
C18H35(OCH2CH2)nOH, n~20
CAS-Nummer:
9004-98-2
Molekulargewicht:
1149.53
MDL-Nummer:
MFCD00074369
UNSPSC-Code:
12162002
NACRES:
NA.23

Beschreibung

non-ionic

Qualitätsniveau

200

Mol-Gew.

average Mn ~1,150

Methode(n)

cell culture | mammalian: suitable
protein quantification: suitable

mp (Schmelzpunkt)

25-30 °C (lit.)

HLB

15

InChI

1S/C20H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h9-10,21H,2-8,11-20H2,1H3/b10-9-

InChIKey

KWVPFECTOKLOBL-KTKRTIGZSA-N

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Allgemeine Beschreibung

Brij® O20 is a non-ionic surfactant that has an 18 carbon tail with a single double bond and the head contains 20 ethylene oxide moieties. It is polyethoxylated fatty alcohol that is hydrophilic in nature.

Anwendung

Brij® O20 has been used:
  • as a detergent in medium A to prepare single detergent micelle aggregates
  • along with phosphate buffer saline (PBS) solution as the receptor solution for terbinafine (TBF) for in vitro permeation studies of TBF-free base in porcine skin
  • as a detergent to isolate detergent-resistant membranes from the mouse brain and to determine the distribution of major mammalian brain gangliosides, GM1, GD1a, GD1b and GT1b

Rechtliche Hinweise

Brij is a registered trademark of Croda International PLC

Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

H-Sätze

H315 - H411

Gefahreneinstufungen

Aquatic Chronic 2 - Skin Irrit. 2

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

464.0 °F - Equilibrium method

Flammpunkt (°C)

> 240 °C - Equilibrium method

Persönliche Schutzausrüstung

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

461199

2,4,7,9-Tetramethyl-5-decin-4,7-diolethoxylat

Brij® L23 main component: tricosaethylene glycol dodecyl ether

Sigma-Aldrich

16005

Brij® L23

Brij® 35 for synthesis

Sigma-Aldrich

8.01962

Brij® 35

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Quality by design (QBD) refers to the achievement of certain predictable quality with desired and predetermined specifications. A very useful component of the QBD is the understanding of factors and their interaction effects by a desired set of experiments. The
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International journal of pharmaceutics, 361(1-2), 222-229 (2008-06-26)
Cyclosporine A (CyA) is an immunosuppressant drug that is used for treating a variety of ocular diseases and disorders. CyA is commonly delivered via eye drops, which is highly inefficient due to a low bioavailability of less than 5%. The
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