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Merck

219827

Sigma-Aldrich

(S)-(−)-2-Hydroxyisocapronsäure

98%

Synonym(e):

2-Hydroxy-4-methylvaleriansäure, L-2-Hydroxy-4-methylpentansäure, L-Leucinsäure

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About This Item

Lineare Formel:
(CH3)2CHCH2CH(OH)CO2H
CAS-Nummer:
Molekulargewicht:
132.16
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
51113400
PubChem Substanz-ID:
NACRES:
NA.22

Qualitätsniveau

Assay

98%

Form

powder

Optische Aktivität

[α]22/D −26.3°, c = 1 in 1 M NaOH

mp (Schmelzpunkt)

78-80 °C (lit.)

SMILES String

CC(C)C[C@H](O)C(O)=O

InChI

1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/t5-/m0/s1

InChIKey

LVRFTAZAXQPQHI-YFKPBYRVSA-N

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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L-Leucin reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

L-Leucin

Fernanda U Fontella et al.
Metabolic brain disease, 17(1), 47-54 (2002-03-16)
In this study we investigated the in vitro effects of the metabolites accumulating in maple syrup urine disease on lipid peroxidation in brain of young rats. Chemiluminescence and thiobarbituric acid-reactive substances were measured in brain homogenates from 7- and 30-day-old
Takayoshi Awakawa et al.
Nature communications, 9(1), 3534-3534 (2018-09-01)
Reprogramming of the NRPS/PKS assembly line is an attractive method for the production of new bioactive molecules. However, it is usually hampered by the loss of intimate domain/module interactions required for the precise control of chain transfer and elongation reactions.
Charles H Lang et al.
American journal of physiology. Endocrinology and metabolism, 305(3), E416-E428 (2013-06-13)
Muscle disuse atrophy is observed routinely in patients recovering from traumatic injury and can be either generalized resulting from extended bed rest or localized resulting from single-limb immobilization. The present study addressed the hypothesis that a diet containing 5% α-hydroxyisocaproic
Antti A Mero et al.
Journal of the International Society of Sports Nutrition, 7, 1-1 (2010-01-07)
Alfa-Hydroxy-isocaproic acid (HICA) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. According to the clinical and experimental studies, HICA can be considered as an anti-catabolic substance. The present study investigated the effects
H M Liebich et al.
Journal of chromatography, 309(2), 225-242 (1984-08-10)
Hydroxy- and oxomonocarboxylic acids in urine of healthy individuals and of patients with diabetic ketoacidosis are analysed as methyl esters and methyl esters/O-methyloximes, respectively, by gas chromatography and gas chromatography-mass spectrometry. The derivatives are pre-fractionated by thin-layer chromatography. The acids

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