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202371

Sigma-Aldrich

Poly(ethylenglykol)

average Mn 300

Synonym(e):

PEG

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About This Item

Lineare Formel:
H(OCH2CH2)nOH
CAS-Nummer:
25322-68-3
MDL-Nummer:
MFCD00081839
UNSPSC-Code:
12352104
PubChem Substanz-ID:
24852059

Form

viscous liquid

Qualitätsniveau

200

Mol-Gew.

Mn 285-315
average Mn 300

Brechungsindex

n20/D 1.463

pH-Wert

6-7 (23 °C, at 10 g/l)

Viskosität

5.8 cSt(210 °F)(lit.)

mp (Schmelzpunkt)

−15-−8 °C (lit.)

Dichte

1.125 g/mL at 25 °C

Mw/Mn

1.1 (typical)

Ω-Ende

hydroxyl

α-Ende

hydroxyl

SMILES String

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChIKey

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Allgemeine Beschreibung

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks, PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.

Anwendung


  • PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.: This study demonstrates that polyethylene glycol (PEG) modification significantly enhances the thermostability and inhibitor resistance of Bst DNA polymerase, highlighting PEG′s potential in improving enzyme performance for biotechnological applications (Yang et al., 2024).

  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: The incorporation of PEG in the lyophilization process of a cell-free protein expression system demonstrates its role in enhancing the stability and efficiency of biotechnological workflows (Alfaro-Palma et al., 2024).

  • A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer.: This review highlights the application of PEGylated nanomaterials in photodynamic therapy, emphasizing its significance in improving biocompatibility and therapeutic efficacy in cancer treatments (Singh et al., 2024).


Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

428.0 °F - closed cup

Flammpunkt (°C)

220.00 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves

Analysenzertifikate (COA)

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Poly(ethylenglykol) average mol wt 400

Sigma-Aldrich

P3265

Poly(ethylenglykol)

Poly(ethylenglykol) BioUltra, 600

Sigma-Aldrich

87333

Poly(ethylenglykol)

Kollisolv® PEG E 400

Sigma-Aldrich

06855

Kollisolv® PEG E 400

Polyethylenglycol 400 United States Pharmacopeia (USP) Reference Standard

USP

1546445

Polyethylenglycol 400

Poly(ethylenglykol) average Mn 6,000

Sigma-Aldrich

81260

Poly(ethylenglykol)

Dimethylsulfoxid ≥99.5% (GC), suitable for plant cell culture

Sigma-Aldrich

D4540

Dimethylsulfoxid

Plasticizing collagen hydrolysate with glycerol and low-molecular weight poly(ethylene glycols)
Langmaier F, et al.
Thermochimica Acta, 469(1-2), 52-58 (2008)
Developing perylene diimide based acceptor polymers for organic photovoltaics
Liang Z, et al.
Synthetic Metals, 161(11-12), 1014-1021 (2011)
Anju Singh et al.
Scientific reports, 10(1), 3766-3766 (2020-03-01)
Th17 cells are critical drivers of autoimmune diseases and immunopathology. There is an unmet need to develop therapies targeting pathogenic Th17 cells for the treatment of autoimmune disorders. Here, we report that anxiolytic FGIN-1-27 inhibits differentiation and pathogenicity of Th17
Rheological studies of disulfonated poly(arylene ether sulfone) plasticized with poly(ethylene glycol) for membrane formation
Oh HJ, et al.
Polymer, 55(6), 1574-1582 (2014)
Ofer Beharier et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27319-27328 (2020-10-23)
The recently identified ferroptotic cell death is characterized by excessive accumulation of hydroperoxy-arachidonoyl (C20:4)- or adrenoyl (C22:4)- phosphatidylethanolamine (Hp-PE). The selenium-dependent glutathione peroxidase 4 (GPX4) inhibits ferroptosis, converting unstable ferroptotic lipid hydroperoxides to nontoxic lipid alcohols in a tissue-specific manner.
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