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191892

Sigma-Aldrich

Hydroxypropylcellulose

average Mw ~370,000, powder, 20 mesh particle size (99% through)

Synonym(e):

HPC

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About This Item

CAS-Nummer:
9004-64-2
MDL-Nummer:
MFCD00132688
UNSPSC-Code:
12162002
NACRES:
NA.23

Beschreibung

biological oxygen demand (BOD) 14,000 ppm

Qualitätsniveau

100

Form

powder

Selbstzündungstemp.

752 °F

Mol-Gew.

average Mw ~370,000

Verunreinigungen

<5 wt. %

Partikelgröße

20 mesh (99% through)

pH-Wert

5.0-8.5

Grenzflächenspannung Mineralöl

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

Viskosität

150-400 cP, 2 wt. % in H2O(25 °C, Brookfield, spindle #2) (60 rpm)(lit.)

Löslichkeit

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

Dichte

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChIKey

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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Allgemeine Beschreibung

Hydroxypropyl cellulose (HPC) is a nonionic derivativeof cellulose. It is a thermosensitive, biodegradable polymer with low criticalsolution temperature.

Anwendung

Hydroxypropyl cellulose can be used to prepare composite nanospheres for drug delivery systems. Hydroxypropyl methacrylate/hydroxy cellulose graft copolymers can be used as matrices for controlled-release tablets. It can also be used as an electrolyte additive to prepare gel polymerelectrolytes for dye-sensitized solar cells.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Satomi Onoue et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 492-499 (2012-04-14)
The present study was undertaken to develop a solid self-emulsifying drug delivery system of coenzyme Q(10) (CoQ(10)/s-SEDDS) with high photostability and oral bioavailability. The CoQ(10)/s-SEDDS was prepared by spray-drying an emulsion preconcentrate containing CoQ(10), medium-chain triglyceride, sucrose ester of fatty
Jianjun Yang et al.
International orthopaedics, 37(3), 515-521 (2012-11-28)
The aim of this study was to determine whether hydroxypropylcellulose (HPC) coating of polyethylene terephthalate (PET) artificial ligaments enhances graft osseointegration in the bone tunnel. Thirty New Zealand white rabbits underwent artificial ligament graft transplantation in the bilateral proximal tibia
Alexandre Monteiro et al.
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
Ranjit M Dhenge et al.
International journal of pharmaceutics, 438(1-2), 20-32 (2012-09-11)
The present work focuses on the study of the progression of granules in different compartments along the length of screws in a twin screw granulator (TSG). The effects of varying powder feed rate; liquid to solid ratio and viscosity of
Hyemin Choi et al.
Journal of pharmaceutical sciences, 101(8), 2941-2951 (2012-05-26)
Living organisms secrete minerals composed of peptides and proteins, resulting in "mesocrystals" of three-dimensional-assembled composite structures. Recently, this biomimetic polymer-directed crystallization technique has been widely applied to inorganic materials, although it has seldom been used with drugs. In this study
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